Diabetes Milk Powder

Blood-glucose control milk powder for diabetes care passes Phase IIA trials

2007-07-27T19:14:00.000-07:00

(BiotechEast staff)14 April, 2004

Local newspaper The China Times reported today that a new method of blood-glucose control had proven effective in Phase IIA clinical trials in Taiwan.

Called Glucose Tolerance Factor (GT&F), the product is a modified milk power, the invention a result of collaboration between National Chunghsing University and local company Maxluck Biotech Corp.

The coordinator of the research team that invented GT&F, Chunghsing Associate Professor Frank Chinhung Mao, said that the university and Maxluck began cooperation three years ago, with GTF the result of two years intensive research and effort.

The group selected for the clinical trial were type II diabetes mellitus patients. This type of diabetes accounts for 95 percent of all diabetes cases, according to Mao. The two-year, 156-patient trial was conducted at 4 local universities; National Taiwan University Hospital, Taichung Veteran's General Hospital, National Chingkung University Hospital, and Tri-service General Hospital.

Mao stated that after four months of consuming GT&F, trial subjects displayed significant improvements in sensitivity to insulin, which leads to a lowering of blood sugar levels on an empty stomach, with women displaying more obvious improvements. The trial indicated that positive results can be seen within only one or two month's consumption of the milk powder, all without side effects, according to Mao.

Mao said that GT&F, once commercialized, would allow for considerable cost savings for the treatment of diabetes patients.

Technorati Tag: Biotechnology pharmaceutical Diabetes Diabetic Malaysia food supplement Health & wellness GT&F Milk Powder Superferrin Metabolic

Drugs for diabetes and it side effects

2007-07-25T00:25:00.000-07:00

There is no drugs to cure diabetes at the moment. The main medical treatment is to control it and lower blood sugar level; It is not easy to achieved this unless the patient : 1) Understand the important of control blood sugar level. 2) He must have strong willpower to control the desire for food and prevent excessive eating and drinking 3) Frequently consult the diabetic specialist, eye specialist, diet therapist and foot therapist, sothat the patient understands his/her condition clearly, that is, whether his/her condition is under controlled.

The goal is to control the patient’s blood sugar level

Director General of Health Services Malaysian Armed Forces in Health Services Division of Headquaters MAF, Ministry of Defence, Mejar Jeneral Dato' (Dr) Sulaiman bin Abdullah in a recent interview stated that the Diabetic Controland Research Center in UK discover that if diabetes patients able to control his blood glucose level. Then, he able to reduce the risk of "capillaries complication"

Reduce major and minor angiopathy

The centre also find that if diabetic able to control his blood pressure ( less than 130/70mmHg) level, he can reduced the risk of "major capillaries and minor capillaries".

The centre stress that diabetic patients must pay close attention to their vision and check whether they are suffering from rethinopathy.

Maj Gen Dato (Dr) Sulaiman Bin Abdullah also mentioned that the Diabetics foot is another important issue. They should consult foot specilists frequently to check the condition of their foot on:

Prickling pain

Ulcers or dead muscle

Neuropathy of the legs

Diet Control

One method to control diabetes and lower blood glucose levels is diet control:

1) Reduce intake of high calories food to reduce the accumulation of fats in the body and maintain ideal weight.

2) Reduce intake of fatty food to delay the development of Atherosclerosis .

3) Reduce intake of sugary food to prevent increase in blood glucose level

4) Increase intake of vegetables, especially high-fiber vegetables, to help to reduce blood sugar levels. In the meantime, this also prevents the sudden decrease in blood sugar because the sudden decrease in blood sugar will result in Hypoglycaemia.

Blood Glucose reducing drugs

There are a few type of drugs that reduce blood sugar levels and the most important drugs are the Sulphonylureas family and Biguanides family.

Sulphonylureas

The machanism of this type of drugs is replenishing insulin secretion. In other words, the alpha cells of the pancreas in the patients body are still able to secrete low but in adequate amount of insulin. Therefore, this type of drugs augments the secretion of insulin from the pancreas. There are several brand names for this family of drugs but their therapeutic effects are very much the same.

Side effects :

There is a risk of low blood pressure especially in elderly patients who has taking this drug for a long period of time. Therefore, this type of drugs must be prescribed by medical specialists.

This type of drugs encourage weight gain. The condition is worse in obese patients as obesity will increase the insulin resistance in the body. This is because the cells are covered by a layer of fat oil. Thus, it is more difficult for pancreas to open the "door" (receptors) of the cells to allow the blood sugar to enter.

Biguanides

Currently there is only one brand name for this family of drugs, which isl "Metformin". The mode of action of this drug is reducing the source of blood sugar, which is also assisting insulin to allow more blood sgar to enter into the cells. At the same time, this drug can also strengthen the tissues in the human body sothat more blood sugar can be utilized. This type of drug has the following benefits:

1) Suitable for type 2 diabetic patient

2) Suitable for obese diabetic patient. This drug is the first line medicine used by obese diabetic patients.(Translator note:Anorexic—Because of this function, Biguanides suitable for obese patients to cause them to reduce their food intake, lower their body weight, and improve the peripheral function of insulin.)

Side effects:

The side effect of this type of drug is the discomfort in the stomach and intestines. Hence, this drug should be taken after meal. However, those with kidney disorder should not take this type of drugs.

Thiazolidinediones

This type of drugs is able to enhance sensitivity of insulin. In other words, it helps blood sugar to enter into cells more easily. If Sulphonylureas and Biguanides mentioned above fail to reduce blood glucose level effectively, then thiazolidinediones drugs should be used.

Acarbose

Blood glucose levels definitely increase after the patients has eaten meal. This type of drugs is able to reduce the blood glucose levels increased after a meal.

Side effect: The side effect is sometimes the drug might cause flatulence

Insulin

Nearly 25% of diabtic patients need to inject insulin. It is a type of Polypeptide Hormone. When insulin comes into contact with gastric acid, it become ineffective. Therefore, the patients have to inject into body directly.

After Insulin injection, the patients should monitortheir blood glucose levels. The blood glucose level after meal should between 4 to 9 mm01/L. Most patients should use insulin of mid-term effects and with two injections per day.

The drugs mentioned above are different methods to reduce the blood glucose in diabetic patients. Although they have high therapeupic effects, each type of drugs does have their side effects.

Glossary

Doule bind

Double-blind test ia a special experimental condition where both the principal investigators (or doctors) and participants (or patient) do not know the nature, procedure and whether the treatment given contains the real medicine, or is merely made up of placebo's hence both are blind, so that any placebo effects and cues during the process of the experiment are eliminated or prevented.

Glucose Tolerence Factor and Diabetes

Glucose Tolerance Factor (GTF) is found in our body tissues and cells. Its main function is to maintain normal glucose metabolism in the body. Glucose Tolerance Factor (GTF) also known as “insulin booster.” Insulin must interact with GTF and insulin receptor to successfully send glucose into cells so it can be converted to energy. GTF is a compound consist of trivalent chromium plus minerals, vitamin, and amino acids

Long term insufficient trivalent chromium intake will result in the decrease of GTF synthesis in our body, and glucose will not be transported into the cells efficiently. Thus, insulin resistance and clinical symptoms of diabetes develop. The presence of excess glucose in the urine will use up more glucose tolerance factor. This lead to serious trivalent chromium deficiency and the gradual loss of kidney functions. This is also one of the main reasons diabetic patients suffer from kidney disorder.

Insufficinet trivalent chromium may cause insulin resistance, affecting glucose and lipid metabolism. Other than diabetes, it will also cause clinical symptoms such as abnormal blood lipid levels and cardiovascular diseases.

GT&F Milk Powder

On 15 January 2006. Malaysia visiting group made a trip to Taiwan to learn about the development of a milk powder that was manufactured diabetic patients - GT&F Milk Powder which contains Glucose Tolerence Factor ( GTF ).

Dr. Kuo Shi-Wen,Director of Division of Metabolism and Endocrinology at Buddhist Xindian Tzu Chi General Hospital, Taiwan has. as a team leader, conducted a Double-blind test on GT&F milk powder. The result is very encouraging. 156 male and female Type 2 diabetes paticipant in the test. After taking GT&F milk powder for 4 months. Majority of the patient's "Insulin Resistance" symptom has been lower. The clinical test has shown that GT&F® Milk Powder is effective in lowering fasting plasma glucose in diabetes patients.

The Clinical Test Results has received compliment from The 25th Annual Meeting of The Endocrinology Society and The Diabetes Association of The R.O.C. 2004.

Beside that, the results were also recognised and published by International Journal of Clinical Practice.

Taiwan National Chung Hsing University Trial

President of Taiwan National Chung Hsing University, Dr. Jei-Fu Shaw(pic), who has a Ph.D. (Biochemistry) from University of Arkansas (1977), and is also a Fellow Member of American Association for the Advancement of Science(AAAS).

The university conducted an experiment on mouse by using GT&F Milk Powder. After 4 months, they also discover that GT&F Milk Powder is able to control diabetes from deterioration reduce blood glucose level without any side effect.

Excerpt and translated from Sin Chew Daily dated 21 March 2006 (Part 2)

Part 1: Diabetes and Diabetes Complications
Part 3 : Unhealthy Food Cause Heart Diseases Easily

Technorati Tag: Biotechnology pharmaceutical Diabetes Diabetic Malaysia food supplement Health & wellness GT&F Milk Powder Superferrin Metabolic

Why Modern People Get Diabetes Easily

2007-07-17T20:38:00.000-07:00

Medical Doctor of Polyclinic & Surgery in Kuala Lumpur Dr. Khor Yeng Kim has numerous years of experience in diabetic treatment. In an exclusive interview by Sin Chew Daily, Dr Khor spoke about the latest discovery in diabetic treatment. Previously, diabetes patients usually comprise of elderly and people with obesity. The current trend is, diabetes patients including young people with slim body. Why a healthy looking people from appearance discover that they have diabetes after blood test? "The main reason is our lifestyle, work and diet have change tremendously. Previously, people labor in farm or factory. Now, majority of people, especially youth work as white collar in office with air-conditioner whole day.They commute with motor vehicle. They lack of exercise, after some year with such lifestyle. They get diabetes." Why such comfort lifestyle can get diabetes. the main reason is insufficient exercise would cause change in metabolism of glucose in our body. In this modern society, no matter you are employed or running your own business, you would face enormous pressure. Pressure cause our glucose level instable.

A lot of modern food, especially cake, cookies and can drink have excessive sugar. If eat frequently, might cause unstable glucose level in our body and reduced glucose metabolism by insulin.
If the above occur, our body would consume a large amount of a trace element call "Glucose Tolerance Factor" (GTF). When our body consume a large amount of "Glucose tolerance Factor" in a long period of time, we would get diabetes.
Some people with serious illness, discover that they get diabetes after a blood test. People give birth to a few baby or give birth to obesity baby, would get diabetes more easily. Why, because, GTF Trivalent Chromium in their blood has been consumed in large amount.
Other than trace element call GTF, our body need another element call Trivalent Chromium to enable our body to control blood glucose in normal level. What is the different between "Glucose tolerance Factor" and Trivalent Chromium?

The answer is: "Glucose tolerance Factor" is a complex material containing a core of amino acids, vitamin and trivalent chromium. The main function of "Glucose tolerance Factor" is to boost the biological activity of insulin and activate insulin receptors to successfully send glucose into cells so it can be converted to energy. If people lack "Glucose tolerance Factor". Glucose unable to absorb into our cells and get diabetes.

Source of Trivalent Chromium

Where we get Trivalent Chromium? We can get Trivalent Chromium from a number of source: One is from the skin of rice, wheat or oats. However, rice that we eat daily has been process and its skin has been loss. If we compare coarse rice and rice that we eat daily. Coarse rice comprise more nutrient than rice by 10 times. Thus, if we eat coarse rice frequently. We able to increase trivalent chromium in our body

Loss of Trivalent Chromium

People eat excessive meat, protein and sugar in their daily life. This cause loss of trivalent chromium during metabolism. The following situation would occur: When our body absorb lesser and lesser trivalent chromium through diet, but increase in loss of trivalent chromium. Diabetes would occur. This is the reason why diabetes become a common sickness nowaday.

Elderly, Obesity- The favorite of diabetes

Trivalent chromium decrease with age
Dr Khor explained: Scientific research discover that trace element of trivalent chromium in the body would reduce when people age. Elderly people have difficulties to absorb trivalent chromium through normal diet. When body have insufficient trivalent chromium, our body unable to produce sufficient "Glucose tolerance Factor" to enable insulin to transport glucose to cell.

Obesity beware

Obesity are another cause of diabetes. Modern people surrounded with good food but exercise less, they become obesity after in this situation for long period of time. Thus, the chance of getting diabetes become higher. When people grow fat. Lipid would cover our body cell. This cause close of insulin receptor. When insulin unable to open the gateway to cell. Glucose unable to transport to cell. And insulin resistance occur occasionally. In this situation, glucose remain circulating within our blood. When our blood glucose level increase, we will get diabetes.

Trial of trivalent chromium

Dr Khor stress that trivalent chromium play an important role in improve normal metabolism of blood glucose, protein and lipid in our body. It also enhance our apatite causing our craving for food or sweets are lesser. Not long time ago, Dr. Stephen Davies in England has conducted the following clinical trial:

Total of 4,872 patients participate.
Elderly patients have lesser trivalent chromium in their serum.
Baby have 0.5ng/ml of trivalent chromium in their body. It reduced when they age, become 0.3ng/ml when they 70 years old. Middle age people have 0.4ng/ml of trivalent chromium in their body. Diabetes type 2 patients have 0.2ng/ml trivalent chromium in their body.
After taking chromium supplement, health of elderly become improve substantially.
After taking chromium supplement, blood glucose level of diabetes type 2 patient reduced to control level.

Trivalent Chromium able to protect your heart

April 2005 issue of American Heart Journal has published a news on trivalent chromium:
According to scientist research: If Type 2 Diabetes take chromium supplement on daily basis, other than able to lower their blood glucose level, this able to protect their heart. This is because trivalent chromium able to lower the QTc interval patients with type 2 diabetes mellitus. Thus, lower their risk of cardiovascular disease.

When a person heart have long QTc interval, He would get Arrhythmias. But if the patients take chromium supplement, it will regularise it heart and thus lengthern the lift spand of type 2 diabetes mellitus.

Dr Bojan, Cardiologist in Ljubljana University Medical Centre in US has reveal recently that:
In the above clinical trial, 30 patients with type 2 diabetes mellitus received 1000 μg of chromium picolinate (CrPic) daily for 3 months, followed by placebo in the next 3 months, this is group A.

Group B, also 30 patients, was treated with placebo for the first 3 months and in the following 3 months with chromium picolinate.

Lower risk of getting Heart disease

At the beginning of the trial, QTc interval was similar between Group A and Group B. Group A 422 milliseconds and Group B 425 milliseconds.

After 3 months, Group A patients who take chromium supplement QTc has shortern to 406 milliseconds. And Group B patients who take chromium supplement QTc has shortern to 407 milliseconds.

The above trial has proved that Type 2 diabetes mellitus who take chromium supplement has lower risk of getting heart Disease.

Obvious Lower in Blood Glucose Level

They also discover: Patients able to lower their blood glucose level after taken chromium supplement of 3 months.

Excerpt and translated from Sin Chew Daily dated 24 March 2006 (Part 5)

Part 4: A New Explanation For Diabetes

Part 1: Diabetes and Diabetes Complication

Technorati Tag: Biotechnology pharmaceutical Diabetes Diabetic Malaysia food supplement Health & wellness GT&F Milk Powder Superferrin

Penerangan Terbaru Mengenai Kencing Manis

2007-07-17T20:24:00.000-07:00

Kencing manis merupakan penyakit kronik, dengan mekanismenya yang menyebabkan penyakit yang tidak diketahui dan tidak boleh diubati selama-lamanya. Walaupun langkah-langkah pengawalan meallui diet, senaman dan ubat-ubatan selama bertahun-tahun dilakukan, keadaan pesakit diabetis masih teruk. Oleh itu, ramai pakar perubatan yang telah berusaha keras untuk mencari penawar mengubati dan merawat diabetis. Walaupun diabetis tidak boleh diubati selama-lamanya, "Susu Tepung GT&F" iaitu satu produk kesihatan baru yang diselidiki dan dibangunkan di Taiwan telah menjadi alternatif kepada pesakit diabetis dan mereka yang berisiko tinggi menghidapinya.

Tiada sebarang ubatan yang berkesan untuk mengatasi diabetis. Ianya hanya bergantung kepada diet yang terkawal dan senaman yang kerap. Jika kaedah ini gagal, bantuan luaran melalui penggunaan ubat diperlukan.

Ketika ini, terdapat lima jenis ubatan yang digunakan untuk mengawal tahap gula darah para pesakit. Jenis ubatan yang pertama merencatkan penghasilan glukosa dalam hati dan jenis ubatan yang kedua berperanan untuk merangsang perembesan insulin. Jenis ubatan yang ketiga pula mengurangkan kerintangan insulin terhadap badan manakala jenis ubatan yang keempat meningkatkan perembesan dan kehilangan insulin ketika penyakit menyerang pesakit. Jenis ubatan yang kelima pula merencatkan pemecahan karbohidrat di dalam usus kecil, justeru penyerapan gula dapat dikurangkan.

Walaupun semakin banyak ubatan dikaji dan dihasilkan sejak beberapa tahun kebelakangan ini, para pesakit kelihatan kurang mengalami simptom tetapi masih tidak dapat mengubati penyakit ini sepenuhnya. Selapas mengambil ubatan, terdapat sebilangan pesakit diabetis Jenis ll yang mengalami ketidakupayaan mengawal keadaan. Bagi menangani kesan ini, rawatan menggunakan suntikan insulin diperlukan.

Laluan terbaru

Diabetis Jenis ll, merupakan penyumbang kes diabetik paling banyak, dan bukan disebabkan oleh kekurangan insulin. ianya hanya disebabkan penurunan reseptor sensitiviti insulin yang mengakibatkan sel tidak berupaya memetabolismekan glukosa. Walaupun dos insulin dipertingkatkan, kesan pemulihan masih terhad.

Pakar berpendapat bahawa tahap gula darah yang tinggi hanya merupakan satu simptom. Faktor yang penting adalah "gula tidak dapat masuk ke dalam sel". Kesannya, "penawar yang kekal dapat membantu penyerapan gula".

Bagaimana untuk meningkatkan bioactivity insulin dan sensitivity reseptor insulin merupakan penyelidikan terbaru untuk mencari rawatan diabetik terkini. Peyelidikan "Faktor Toleransi Glukosa" merupakan salah satu daripadanya.

Faktor Toleransi Glukosa terdapat didalam tisu dan sel. Fungsi utamanya adalah untuk menyelenggarakan metabolisme gula dalam badan, dan berkerjasama dengan insulin untuk mengangkut gula dari darah ke dalam sel dalam badan.

Seawal tahun 1957, pakar biologi Amerika Dr. Walter Mertz dan Dr. Klaus Schwarz telah menemui Faktor Toleransi Glukosa di dalam buah pinggang khinzir. Kemudian, ianya terbukti bahawa unsur ini yang mana mengandungi vitamin, asid amino dan trivalen kromium merupakan molekul yang diperlukan untuk mengaktifkan reseptor insulin. Ia mempunyai kesan penurunan gula darah dan trivalen kromium merupakan kunci elemen tersebut.

Amaun surih kromium terdapat dalam badan manusia. Kromium paling banyak terkumpul di tulang sum-sum tetapi tahap kromium berkurangan dengan peningkatan umur. Pengambilan kromium amat serius dan sangkat diperlukan dalam keadaan terutamanya obesiti, mengandung, ketagihan arak, terlampau berkerja dan mengalami tekanan yang berlebihan.

Tidak mudah untuk mendapatkan semula kromium. Kromium terdapat dalam susu awal ibu, hati dan buah pinggang haiwan serta dalam makanan pula seperti bunga kobis, kentang, anggur dan oren. Walau bagaimanapun, kromium yang bersala daripada sumber ini tidak mudah diserap kerana selepas dimakan, ianya mudah bergabung dengan fiber (serat) dalam salur gastrointestinal (saluran usus) dan dikeluarkan dari badan melalui feces (najis).

Mencegah lebih baik daripada mengubati

Sebagai produk penjagaan kesihatan, objektif yang diharapkan kepada "Susu Tepung GT&F" adalah untuk mengawal atur fungsi fizikal dan meningkatkan metabolisme. Sasaran tidak terhad kepada pesakit diabetik sahaja.

Selain daripada pesakit diabetik, penjagaan yang lebih sepatutnya diberikan juga kepada kumpulan berisiko tinggi yang mederita obesiti (kegemukan) dan penyakit keturunan. Pakar mengeluarkan kenyataan bahawa keadaan tubuh seseorang tidak sepatutnya dipandang remeh. Oleh itu, kita sepatutnya menjaga kesihatan dari segenap aspek.

"Rawatan terbaik adalah sebelum penyakit menulat". Kenyataan ini amat benar dalam kita mendepani panyakit epidemik pada abad ke-21 ini....Kencing Manis.

Terjemah dari Sin Chew Jit Poh bertarikh 23hb Mar 2006. (Bahagian 4 Side Par)

Bahagian 4: Susu Tepung GT&F boleh menurunkan gula darah

Technorati Tag: diabetis diabetik Diabetes Kencing Manis Malaysia

A New Explanation For Diabetes

2007-07-06T00:35:00.000-07:00

Diabetes is a chronic disease, with the mechanism for the cause of the disease unknown, and cannot be cured permanently. Despite controlling their conditions by diet, exercise and drugs for years and years, the conditions of some diabetics patients still deteriorate. Therefore, those in the medical field have been trying very hard to search for a cure to treat diabetic patients. Although cannot cure diabetes permanently, "GT&F Milk Powder", a health care product recently researched and developed in Taiwan, provides an alternative for patients and the high risk group.

There is no efficacious medicine to deal with diabetes. It only depends on the patients' own diet control and regular exercise. If all of these fail, external help by using drugs is required.
Currently, there are five types of drugs that are used to control the blood sugar levels in the patients. The first kind of drug inhibits the production of glucose in the liver and the second type acts by stimulating the secretion of insulin. The third type of drugs reduces the resistance against insulin in the body while the fourth type improves the rapid secretion and losses of insulin when the disease attacks the patients. The fifth type of drug inhibits the break down of carbohydrates in small intestines, so that sugar absorption is reduced.
Although more and more drugs are being researched and develop in recent years, they seemed to be merely alleviating the symptoms rather than curing the disease completely. After consuming drugs, some Type 2 diabetic patients do experience gradual loss of control over their conditions. Thus to improve the effects, treatment by insulin injection is required.

Open Up A New Path

Type 2 diabetes, which accounts for most of diabetic cases, is not caused by insulin deficiency. It is only the decrease in the sensitivity of insulin receptor that makes the cells unable to metabolize glucose. Despite increasing the insulin dosage, the effect is still limited.
Specialists pointed out that high level of glucose in the blood is only a symptom. The crucial factor is " the glucose unable to enter into the cell". Hence, "the permanent cure should be aiding the absorption of glucose".

How to strengthen the bioactivity of insulin and the sensitivity of receptors is a new research direction for diabetic treatment. Research on "Glucose Tolerance Factor" is one of them.
Glucose tolerance factor is present in tissues and cells. The main functions are to maintain the metabolism of glucose in the body, work together with insulin to transport glucose from blood into cells in the body.

As early as in 1957, American biologist Dr. Walter Mertz and Dr. Klaus Schwarz had discovered Glucose Tolerance Factor in mamalian kidney. Later on, it was proven that this compound, which consists of vitamin, amino acid and trivalent chromium, is the essential molecule to activate the insulin receptor. It able to reduce blood glucose level effect, of which, trivalent chromium is the key element.

Trace amount of chromium elements is present in the human body. Chromium is mostly accumulated in the bone marrow but chromium levels reduce with the increase in age. The loss of chromium is more serious under obesity, pregnancy, alcoholism, over work and over stress conditions.

It is not easy to replenish chromium. Chromium is present in the colostrums milk, liver and kidney of animals and in cauliflower, potato, grapes and orange in the food. however, chromium from those sources are not easily absorbed by human body because they are ingested, they combine easily with the fibers in the gastrointestinal tract and are excreted out of body together with faeces.

Prevention and treatment

Position as a health care product, the objective of "GT&F Milk Powder" is to regulate physical functions and enhance metabolism. The target is not limited to diabetic patients only.Besides diabetic patients, special care should be given to obesity and hereditary high risk group.

Specialists pointed out that conditions of the body cannot be clearly cut off by a single line drawn by human. So, before crossing the line, we should take good care of ourselves.

"Prevention is better than cure". this is especially true in dealing with the epidemic disease of the 21st century.........diabetes.

Excerpt and translated from Sin Chew Daily dated 23 March 2006 together with Part 4 of the articles series.

Part 4: GT&F Milk Powder able to lower diabetics' blood glucose level

Part 5: Why Modern People Get Diabetes Easily

Site that link here: Pharmaceutical Market Research

Technorati Tag: Biotechnology pharmaceutical Diabetes Diabetic Malaysia food supplement Health & wellness GT&F Milk Powder Chromferrin

Stem cell transplant promising for type 1 diabetes

2007-05-02T16:24:00.000-07:00

NEW YORK (April 11, 2007): In a small study, a treatment that included stem cell transplantation induced prolonged insulin independence in patients with newly diagnosed type 1, or insulin-dependent, diabetes.

In a statement, lead author Dr. Julio C. Voltarelli, from the Regional Blood Centre in Ribeiro Preto, Brazil, called the results “very encouraging”.

While the same approach has been used in other autoimmune disorders, the current study, to the author’s knowledge, represents the first time the approach has been used in human type 1 diabetes.

In type 1 diabetes, a person’s immune system attacks and destroys insulin-producing beta cells in the pancreas. Preserving beta cells is a key concept in the management of type 1 diabetes and in the prevention of its related complications.

Voltarelli’s team tested the ability of high-dose immune suppression and stem cell transplantation to preserve beta cell function in 15 patients who were diagnosed with type 1 diabetes in the previous 6 weeks. All of them required insulin.

Stem cell transplantation involves the harvesting and treatment of a patient’s own stem cells and then returning them to the patient via intravenous injection.

During follow up, 14 patients became insulin-free - 1 for 35 months, 4 for at least 12 months, and 7 patients for at least 6 months. Two “late responders” were insulin-free for 1 and 5 months, respectively.

The therapy was well tolerated; the only severe side effects were pneumonia in one patient and endocrine dysfunction in two others.

While further study is needed, Dr. Jay S. Skyler, from the University of Miami, comments in a related editorial, “the time may indeed be coming for starting to reverse and prevent type 1 diabetes”. – (SOURCE: Journal of the American Medical Association, April 11, 2007) – Reuters

Diabetes complications swelling U.S. health costs

CHICAGO (April 11, 2007): Poorly managed type 2 diabetes costs the U.S. health system an extra US$22.9 billion a year in direct medical costs to treat heart, eye, kidney and other serious health problems associated with the disease, diabetes groups reported yesterday.

Annual health costs for a type 2 diabetic are three times that of the average American without diagnosed diabetes, according to a new report called State of Diabetes Complications in America.

“It is a pretty significant wake-up call for people, or should be. It really points out the importance of managing the disease,” said Willard Manning, a health economist at the University of Chicago who worked on the report.

About 20.8 million Americans have diabetes, which causes about 5% of all deaths globally each year.

Most have type 2, or adult-onset diabetes, in which the body loses its ability to use insulin.
Obesity and lack of exercise are linked with type 2 diabetes, which can cause blindness, heart disease, stroke, chronic kidney disease and foot problems that can require amputations.

“We have tools today. The fact that people are still getting complications means we are not using our tools effectively enough,” said Dr Daniel Einhorn, who serves on the board of the American Association of Clinical Endocrinologists, which sponsored the report.

Einhorn said diabetes continues to be the leading cause of blindness. Two thirds of people with diabetes get heart disease or stroke, and death rates are two to four times higher in adults with diabetes than without.

COSTLY COMPLICATIONS
Diabetic complications cost almost US$10,000 each year, with US$1,600 of that coming from patients’ own pockets for costs not covered by insurance.

That figure represents quite a bite for many diabetics, nearly 40% of whom had annual income of less than US$35,000 in 2005.

Treating type 2 diabetes alone costs about US$37 billion a year. When people fail to follow their diet, exercise and drug treatment plans, the disease leads to complications that boost the total health bill to US$57.1 billion.

“That is a substantial sum in its own right,” Manning said in a telephone interview.

“When you take into account where some of that is going - heart attacks, strokes, kidney failures - things which lead to either reductions in employment or departures from the labour force ... there is a substantial amount of additional cost.”

The report, released at the American Association of Clinical Endocrinologists’ annual meeting in Seattle, combined data from two large national studies between 1999 and 2004. Cost estimates were adjusted into 2006 dollars.

The report estimates that one out of three people with the disease has one other serious health problem. One in 10 has two other serious health problems. One out of 15 has three other serious health problems, and one out of 13 has four or more.

“If you look at the list of the complications, most of them are there because of poorly managed diabetes,” Manning said.

“Either the patient doesn’t recognise they have it and complications develop, or they are not good about adhering to their doctor’s orders,” he said, adding, “We’ve got to do a better job of managing the disease.” – Reuters

Technorati Tag: Diabetes Diabetic Malaysia food supplement

Pig cells still work in diabetic man after 10 yrs

2007-04-10T22:55:00.000-07:00

HONG KONG (Reuters) - Cells from a pig transplanted into a diabetic man from New Zealand are still producing insulin nearly 10 years later, prompting a biotechnology company to plan research to see if others could benefit.

The case, profiled in a scientific journal issued on Friday, may pave the way for a cure for diabetes, said Bob Elliot, medical director of Australia's Living Cell Technologies (LCT).

The man, now 41, suffers from type 1 diabetes, when cells in the pancreas do not produce insulin -- a hormone needed to store or use sugar. This results in abnormally high sugar levels in the blood, or diabetes, which needs to be corrected with daily insulin injections.

The pig cells were injected into the man's abdomen in 1996, which helped reduce his insulin requirements by 34 percent for a year, researchers from the biotech firm wrote in a paper published in the latest issue of the journal Xenotransplantation.

The man insisted he still felt better in 2006 and convinced the company to examine him.
"A careful examination shows his diabetes control has been a lot better even 10 years after the transplant," Elliot told Reuters.

Tests, which became available only recently, showed that insulin detected in the man's blood were pig insulin, not human insulin, he added.

The company hopes to conduct small-scale clinical trials in Russia and New Zealand in coming months to inject more diabetes patients.

Diabetes Can Kill More People Than Bird Flu, Says Expert

2007-04-10T00:32:00.000-07:00

Oct 24 -- Governments across the region may be rushing to contain the spread of bird flu virus but a health expert warn a much greater health concern that can cost Asian economies up to US$500 million in the next decade is being overlooked.

International Diabetes Institute Director Prof Paul Zimmet said diabetes was far more certain than bird flu to prematurely claim millions of lives.

Similarly, diabetes-related deaths in Asia over the next few decades would dwarf those caused by HIV/AIDS, he said.

"It is not the bird flu or HIV/AIDS, but it is the killer disease (diabetes) that we are not prepared for, with the potential to claim millions of lives," he said in a text released in conjunction with the Sixth International Diabetes Federation conference for Asia being held in Bangkok.

Zimmet said the public cannot be blamed for thinking bird flu would be the major threat for Asia in the coming decades due to wide publicity, huge response from world leaders and scientists.

"After all, an Asia-Pacific Economic Co-operation (APEC) meeting has been called to focus on bird flu, scientists are fretting over a bird flu vaccine, and Asian bird flu casualties are being cited as early signs of potential pandemic," he said.

Zimmet said diabetes posed more direct threat to human population and cited the World Health Organisation's (WHO) recent report that chronic diseases, dominated by diabetes, now cause twice the number of deaths than infections diseases (including HIV), maternal/pre-natal conditions, and nutritional deficiencies combined.

He said in the next decade, the number of global lives claimed by diabetes was set to grow by a quarter, driven by rising obesity and inactivity.

"It could cause the first life expectancy reduction in more than 200 years. And nowhere is the problem more serious than in Asia," said Zimmet, who is also Head of WHO's Collaborating Centre for the Epidemiology of Diabetes.Zimmet said there are now 90 million people with diabetes in Asia and it is home to four of the world's five largest diabetic population -- India (33 million), China (23 million), Pakistan (nine million) and Japan (seven million).

Globally, WHO estimates the diabetes population would grow to more than 200 million in 2010 and 330 million in 2025, said Zimmet, who warned that 60 per cent of global diabetes cases would be in Asia in less than a decade.

"Asia should be in a state of panic. While diabetes can be treated, with limited access to treatments a majority of diabetics will die prematurely."

There is often a misconception that diabetes is not lethal, with deaths often attributed to complications rather than the disease itself," he said.

Zimmet said diabetes puts people at risk of many diseases and premature death as it causes damage to many body tissues and progresses to stroke, heart disease, kidney failure, blindness, susceptibility to serious infections and amputations due to loss of circulation.

One of the major factors that saw diabetes increasing in Asia is progressive westernisation or "Coca-Colonisation" of its countries that has seen the adoption of fatty food diets and sedentary lifestyles, he said.

"Disturbingly, the non-insulin dependant variety of diabetes (type 2) with typical onset in late adulthood in most parts of the world, is surfacing in children in Asia," he said.

With scare health resources, Zimmet said Asia was ill-prepared to tackle diabetes effectively and was likely to be distracted by more immediate threats such as bird flu.

Zimmet said there was no doubt that if bird flu was serious enough to warrant an APEC meeting later this year, a similar meeting on diabetes was long overdue.

-- BERNAMA 2005

Technorati Tag: Diabetes Diabetic Malaysia food supplement

Diabetes Diet

2007-04-10T00:23:00.000-07:00

The proper diet is critical to diabetes treatment. It can help someone with diabetes:

Achieve and maintain desirable weight. Many people with diabetes can control their blood glucose by losing weight and keeping it off.

Maintain normal blood glucose levels.

Prevent heart and blood vessel diseases, conditions that tend to occur in people with diabetes.
A doctor will usually prescribe diet as part of diabetes treatment. A dietitian or nutritionist can recommend a diet that is healthy, but also interesting and easy to follow. No one has to be limited to a preprinted, standard diet. Someone with diabetes can get assistance in the following ways: A doctor can recommend a local nutritionist or dietitian.

The local American Diabetes Association, American Heart Association, and American Dietetic Association can provide names of qualified dietitians or nutritionists and information about diet planning.

Local diabetes centers at large medical clinics, hospitals, or medical universities usually have dietitians and nutritionists on staff.
The guidelines for diabetes diet planning include the following:

Many experts, including the American Diabetes Association, recommend that 50 to 60 percent of daily calories come from carbohydrates, 12 to 20 percent from protein, and no more than 30 percent from fat. Spacing meals throughout the day, instead of eating heavy meals once or twice a day, can help a person avoid extremely high or low blood glucose levels.

With few exceptions, the best way to lose weight is gradually: one or two pounds a week. Strict diets must never be undertaken without the supervision of a doctor.

People with diabetes have twice the risk of developing heart disease as those without diabetes, and high blood cholesterol levels raise the risk of heart disease. Losing weight and reducing intake of saturated fats and cholesterol, in favor of unsaturated and monounsaturated fats, can help lower blood cholesterol.
For example, meats and dairy products are major sources of saturated fats, which should be avoided; most vegetable oils are high in unsaturated fats, which are fine in limited amounts; and olive oil is a good source of monounsaturated fat, the healthiest type of fat. Liver and other organ meats and egg yolks are particularly high in cholesterol. A doctor or nutritionist can advise someone on this aspect of diet.

Studies show that foods with fiber, such as fruits, vegetables, peas, beans, and whole-grain breads and cereals may help lower blood glucose. However, it seems that a person must eat much more fiber than the average American now consumes to get this benefit. A doctor or nutritionist can advise someone about adding fiber to a diet.

Points to Remember

A diabetes diet should do three things; achieve ideal weight, maintain normal blood glucose levels, and limit foods that contribute to hear disease.

A nutritionist or dietitian can help plan a diabetes diet.

Exchange lists are useful in planning a diabetes diet. They place foods with similar nutrients and calories into groups. With the help of a nutritionist, the person plans the number of servings from each exchange list that he or she should eat throughout the day. Diets that use exchange lists offer more choices than preprinted diets. More information on exchange lists is available from nutritionists and from the American Diabetes Association.

Continuing research may lead to new approaches to diabetes diets. Because one goal of a diabetes diet is to maintain normal blood glucose levels, it would be helpful to have reliable information on the effects of foods on blood glucose. For example, foods that are rich in carbohydrates, like breads, cereals, fruits, and vegetables break down into glucose during digestion, causing blood glucose to rise. However, scientists don't know how each of these carbohydrates affect blood glucose levels. Research is also under way to learn whether foods with sugar raise blood glucose higher than foods with starch. Experts do know that cooked foods raise blood glucose higher than raw, unpeeled foods. A person with diabetes can ask a doctor or nutritionist about using this kind of information in diet planning.

Technorati Tag: Diabetes Diabetic Malaysia food supplement

Low-fat dairy linked to lower diabetes risk in women

2007-04-03T21:19:00.000-07:00

By Stephen Daniells

7/7/2006 - A diet rich in low fat dairy could cut the risk of type-2 diabetes for women by over 20 per cent, says a new study from Harvard.

Dairy food makers looking to drill further into the health benefits of their primary foodstuffs will welcome the new findings that appear to fit with previous research for men (May 2005, Archives of Internal Medicine).

Although studies have indicated that increased dairy intake may reduce risk of overweight and insulin resistance syndrome, data directly relating dairy intake to type-2 diabetes remain sparse,explained lead author Simin Liu in the July issue of the journal Diabetes Care (Vol. 29, pp. 1579-1584).

To attempt to fill this void in data, the scientists from Brigham and Women's Hospital, the Massachusetts General Hospital, Harvard School of Public Health, Harvard Medical School, UCLA, and the Center for Disease Control and Prevention tracked 37,183 women for ten years.
The prospective study found that the risk of developing type-2 diabetes was cut by four per cent for each serving-per-day increase in dairy intake.

During the ten years of follow-up, 1,603 women developed type-2 diabetes. After adjusting the data to account for BMI, smoking status, family history of diabetes, high cholesterol and other potential risk factors, the researchers found that women in the highest dairy intake group had a 21 per cent lower risk of type-2 diabetes than the women in lowest dairy intake group.

This beneficial association was apparently attributable to low-fat dairy intake.

A dietary pattern that incorporates higher low-fat dairy products may lower the risk of type-2 diabetes in middle-aged or older women, wrote the researchers.

The mechanism behind the effect is not clear, said the researchers, and further research was necessary to confirm the results and elucidate the active ingredients.

However, when the researchers did adjust for vitamin D, calcium, magnesium, fat and fibre content of the diary products, the association between dairy intake and diabetes risk was still present.

This suggests a potential role for other nutrients in the milk, possibly milk proteins. A report at the end of last year in the American Journal of Clinical Nutrition (vol 82, pp. 972-979) reported that skimmed milk consumption could lower the risk of hypertension, and put the effects down to both caseins and whey proteins in the milk.

t is plausible that saturated fats in whole-fat dairy products somehow neutralize the beneficial effect of dairy protein, said the lead author of the AJCN study, Alvaro Alonso from the University of Navarro in Spain.

Liu and co-workers called for research to continue in this area before any public health measures concerning dairy consumption could be recommended.

An estimated 19 million people are affected by diabetes in the EU 25, equal to four per cent of the total population. This figure is projected to increase to 26 million by 2030.

爱喝牛奶较不易得糖尿病

爱喝牛奶、吃乳酪的人有福了！最新研究表示，富含低脂乳制品的饮食，可能会减低女性罹患第二型糖尿病的风险。这项研究由波士顿布莱根妇女医院Simin Liu医学博士及其同事，将研究结果发表在《糖尿病照护期刊》中。

Liu和同事分析了超过37,000位平均年龄55岁的女性；调查关于她们的饮食习惯，问卷内容涵盖了130种食物和饮料，包括脱脂牛奶、全脂牛奶、乳酸菌、果汁牛奶冻、白干酪、冰淇淋和酸乳酪。其他的资料包括BMI指数、抽烟状况、饮酒、运动与其他饮食因素，停经后荷尔蒙治疗的使用和糖尿病的家族史。

研究开始时，没有人罹患糖尿病，在长达10年的研究期间，有1,603位女性被诊断出糖尿病。饮食中钙摄取量最高的女性，比那些钙摄取量最少的人，较不可能被诊断出罹患第二型糖尿病。

研究人员表示，调整糖尿病风险因子，并不会改变这些结果；因为，这些调查结果对于低脂乳制品是较为强烈，甚至超过高脂乳酷品的项目。

Technorati Tag: Biotechnology pharmaceutical Diabetes Diabetic Malaysia food supplement Health & wellness GT&F Milk Powder Chromferrin 生物科技耐糖因子奶粉 Malaysia GT&F Health 糖尿病

齐来击退糖尿病

2007-04-03T20:02:00.000-07:00

光华日报 [ 健康 ] - 居家保健
2007-4-3 11:07:27

在一项调查约有70万名糖尿病患者，最年轻的只得6岁。据世界卫生组织（WHO）估计，未来20年间，亚洲糖尿病患者人数将激增7成，达致120万人，患病比率亦急升28%，有关的数字实在令人吃惊。

芬兰研究人员完成的一项最新调查，对于糖尿病高风险一族而言，健康的饮食和进行适度运动十分有助预防糖尿病。芬兰国家公共卫生研究所的亚科图奥米莱赫托和同事，对糖尿病高风险一族进行了跟踪研究，在接受调查的500多人中，一半人在饮食和运动上接受有效的指导，包括减少饱和脂肪摄入、多吃含纤维食品、每天运动30分钟等；而另一半人则作为对照组。在连续7年跟这两组受访者之后，研究人员发现，跟从健康生活方式的一组，患糖尿病的风险比对照组低15%至20%。研究人员更认为，注重饮食健康及积极运动等健康生活方式，不但可以降低高风险人群患Ⅱ型糖尿病的风险，还可推迟这些人发病的时间。

此外，亦有以色列的研究人员发现，愈投入工作、压力愈大的人士，愈容易患上Ⅱ型糖尿病，除了健康饮食和适当运动之处，研究人员并建议，打工仔应妥善管理工作上的压力问题，了解工作情况，有需要时可考虑转换工作环境，以减低患上糖尿病的机会。

耐糖因子，第二型糖尿病患者的希望（整理：陈晓云）

缺乏耐糖因子已被证实能导致第二型糖尿病、妊娠糖尿病，及药物引发的糖尿病。此外，它也会引起高胆固醇、周边血管疾病、心脏病、中风、动脉硬塞等各种疾病，因此补充耐糖因子是预防及控制糖尿病，其他疾病的主要方针。

耐糖因子（GTF）是在1957年被世界卫生组织前顾问，美国农业部人类营养研究中心（USDA）前主任Dr.Walter Mertz 所发现。它是一种由三价铬（Trivalent Chromium）维生素与氨基酸组成的复合物。

什么是耐糖因子，GTF？

GTF是GLUCOSE TOLERANCE FACTOR 的缩写，译为中文是耐糖因子。耐糖因子普遍存在于人体的每个细胞，它主要的功能是调节葡萄糖、蛋白质及脂肪的新陈代谢，因而被称为耐糖因子。

耐糖因子是胰岛素的辅助因素，它能刺激胰岛素的生物作用，提高胰岛素受体的敏感性及促进胰岛素与胰岛素受体的结合，使葡萄糖能更有效地进入细胞。相反地，如果体内的耐糖因子不足，血液中的葡萄糖无法进入细胞，这除了会产生高血糖等等临床症状之外，还会使细胞处于能量不足的状态，因此适量补充耐糖因子是从基本上调节血糖的重大突破。

正常人由食物中摄取的三价铬，可在体内转化成GTF，进而协助葡萄糖的正常代谢；惟，在我们饮食中所能摄取的三价铬含量少过20%人体每日所需，此外，真正能被人体所吸收的三价铬只有摄取量的0.5-2%。

根据Dr. Stephen Davies在1997年的研究报告，耐糖因子会随著老化、肥胖、操劳过度、低蛋白质的饮食、怀孕、手术、酗酒和疾病等原因而逐渐减少。当身体缺乏此物质时，葡萄不能够有效地被细胞吸收而积聚在血管内，因而引发更多种的疾病。

Technorati Tag: 生物科技耐糖因子奶粉 Malaysia food supplement GT&F Health Chromferrin 糖尿病

Foot care in diabetes

2007-04-02T22:04:00.000-07:00

DIABETES causes your blood sugar levels to be higher than normal. Over time, high blood sugar levels can damage the blood vessels and nerves in the body. Damage to the nerves means that you may have burning pain or lose feeling in a part of your body (this is called diabetic neuropathy). Damage to the blood vessels means that your feet may not be getting a good supply of blood.

How to avoid problems with your feet

Keep your blood sugar levels as close to normal as possible. Also, follow your doctor’s advice on diet, exercise and medicine. Here are some other ways to protect your feet:

Examine your feet everyday. Examine from the top to the bottom of your foot. Look and feel in between your toes and around the heel area. Look for cuts, sores, blisters, redness, swellings, corns and calluses, ingrown toe nails, changes in skin colour and so on. If you are unable to see your feet, use a mirror or ask someone to help you.

Wash your feet everyday with lukewarm (not hot) water and mild soap.

Do not soak your feet as this will make your skin too soft and fragile.

Do not use rough massage gloves or brushes as they can damage your skin.

Do not wash your feet for too long.

Dry your feet thoroughly with a soft towel and pat gently; don’t rub. Make sure you do not forget to dry between your toes. Damp skin can easily lead to infections.

Dust your feet with talcum powder, which will help keep them dry.

If you have dry skin on your feet, use a moisturising lotion to prevent cracking. Do not apply between your toes, as this may lead to infection.

Keep your toenails trimmed. Trim them with toenail clippers after you have washed and dried your feet. Trim the nails following the shape of your toes, and not too short. Do not cut into the corners of the nail, which may trigger an ingrown toenail. File your toenails with nail file to smoothen them.

Rasps for removing callus, razor blades, pointed scissors and corn plasters are widely used instruments in pedicure. Unfortunately, none of these are suitable for taking care of the feet and nails of people with diabetes, since they can easily cause injuries or damage to the skin. Use a pumice stone to remove callus, especially after washing the feet. Gently rub the stone over the callus in one direction only. Continue to do this for five minutes every day till the callus is being removed.

Always wear sandals when visiting the swimming pool.

Do not go barefoot, even when indoors.

Don’t let your feet get too hot or too cold.

Do foot exercises and massage your feet everyday to stimulate the circulation.

DO NOT go to the foot massage parlour to massage your feet as it may injure them.

If your feet have any cuts or abrasions, clean the wound immediately with saline, apply an antiseptic cream and secure a sterile dressing to the area. Continue with dressing until the wound is healed. Seek medical treatment if the wound does not show any signs of healing after two days.

If you have diabetes, avoid shoes with high heels or pointed toes – such shoes increase pressure and may cause ulcers.

Choosing proper footwear

When buying shoes, a perfect fit should be top priority. A couple of tips may help you to find the right shoes:

Wear well-cushioned (insoles) walking shoes or athletic shoes. They should have leather or canvas uppers, which breathe to keep your feet from getting sweaty.

Do not wear open-toed shoes or sandals with a strap between the first toes.

Footwear should fit both the length and width of the foot, with rooms for the toes.

Avoid shoes with high heels or pointed toes – such shoes increase pressure and may cause ulcers.

When you buy new shoes, get them at the end of the day when your feet are little swollen. If shoes are comfortable when your feet are swollen, they’ll probably be comfortable all day.

Break in new shoes slowly by wearing them for no more than an hour a day for several days.

Always wear socks, or stockings, with your shoes to help avoid blisters and sores. Choose soft socks made of cotton, or cotton-polyester blend, which will help keep your feet dry. Avoid wearing socks that are too tight around your legs as they can constrict circulation to your feet.

Change your socks or stockings every day.

Always check the inside of your shoes for foreign items before wearing them. These items could rub against your feet and cause blisters and sores.

Note: This article is courtesy of Nestle Nutrition

Technorati Tag: Diabetes Diabetic Malaysia food supplement

Vegan diet reverses diabetes symptoms, study finds

2007-04-02T21:59:00.000-07:00

WASHINGTON (Reuters) - People who ate a low-fat vegan diet, cutting out all meat and dairy, lowered their blood sugar more and lost more weight than people on a standard American Diabetes Association diet, researchers said on Thursday.

They lowered their cholesterol more and ended up with better kidney function, according to the report published in Diabetes Care, a journal published by the American Diabetes Association.
Participants said the vegan diet was easier to follow than most because they did not measure portions or count calories. Three of the vegan dieters dropped out of the study, compared to eight on the standard diet.

"I hope this study will rekindle interest in using diet changes first, rather than prescription drugs," Dr. Neal Barnard, president of the Physician's Committee for Responsible Medicine, which helped conduct the study, told a news conference.

An estimated 18 million Americans have type-2 diabetes, which results from a combination of genetics and poor eating and exercise habits. They run a high risk of heart disease, stroke, kidney failure, blindness and limb loss.

Barnard's team and colleagues at George Washington University, the University of Toronto and the University of North Carolina tested 99 people with type-2 diabetes, assigning them randomly to either a low-fat, low-sugar vegan diet or the standard American Diabetes Association diet.

After 22 weeks on the diet, 43 percent of those on the vegan diet and 26 percent of those on the standard diet were either able to stop taking some of their drugs such as insulin or glucose-control medications, or lowered the doses.

The vegan dieters lost 14 pounds (6.5 kg) on average while the diabetes association dieters lost 6.8 pounds (3.1 kg).

An important level of glucose control called a1c fell by 1.23 points in the vegan group and by 0.38 in the group on the standard diet.

DROPPING DRUGS

A1c gives a measure of how well-controlled blood sugar has been over the preceding three months.

In the dieters who did not change whatever cholesterol drugs they were on during the study, LDL or "bad" cholesterol fell by 21 percent in the vegan group and 10 percent in the standard diet group.

The vegan diet removed all animal products, including meat, fish and dairy. It was also low in added fat and in sugar.

The American Diabetes Association diet is more tailored, taking into account the patient's weight and cholesterol. Most patients on this diet cut calories significantly, and were told to eat sugary and starchy foods in moderation.

All 99 participants met weekly with advisers, who advised them on recipes, gave them tips for sticking to their respective diets, and offered encouragement.

"We have got a combination here that works successfully," said Dr. David Jenkins of the University of Toronto, who worked on the study. "The message that we so often get with diet is that it is no good because nobody follows it for very long."

Dr. Joshua Cohen, George Washington University associate professor of medicine, said everyone diagnosed with diabetes is told to start eating more carefully.

"That may be among the hardest things that any of us can do," Cohen told the news conference.
The vegan diet "is at least as good, if not better than traditional approaches," Cohen said.
Vance Warren, a 36-year-old retired police officer living in Washington, said he lowered his a1c from 10.4, considered uncontrolled diabetes, to 5.1, considered a healthy level, over 18 months. "My life is much better being 74 pounds (34 kg) lighter," Warren told the news conference.

By Maggie Fox, Health and Science Correspondent

Technorati Tag: Diabetes Diabetic Malaysia food supplement

Diabetes

2007-03-21T00:40:00.000-07:00

By: guardian

This is a condition in which the body cannot use or store sugar normally. This increases the sugar levels in the body, which produces the symptoms below. Over time the condition can lead to complications affecting the organ systems including the kidney and eyes. Adult onset of diabetes is often associated with poor diet and obesity.

Symptoms

Passing increased amounts of urine, both day and night
Increased thirst
Sometimes a loss of weight
Fatigue
Disturbed vision - usually blurring
Recurrent skin infections

Many of the complications of diabetes will give no obvious symptom until the problem is well advance and the damage is done. Complications of long term diabetes includes more serious problems such as blindness, loss of mobility, increased risk of heart attacks and kidney failure.

Home care for diabetes

Weight management is the cornerstone of diabetic treatment. The patient should keep to his recommended body weight by eating a diet low in fats and rich in the proper carbohydrates. He needs to control his intake of refined sugar.
Regular exercises will help to burn blood glucose and body fat.
Elderly diabetics must take particular care of their feet and legs because circulation is poor, causing the skin to be thin and devitalised. A small cut or sore can lead to serious infections if not tended to properly.
Practise good hygiene.

Related Articles

- Hypoglycaemia (Low Blood Sugar)

- Diabetic Complications

- Control of Blood Glucose Level

- Blood Glucose Test

Diabetic Complications

What is Diabetes

Diabetes mellitus or more commonly called diabetes is a condition where there is an absence or inadequate secretion of insulin. Insulin is a hormone made in an organ in our body called the pancreas. The function of the insulin in the body is to absorb the glucose from our diet and turn it into energy.

In a diabetic patient, the pancreas does not produce enough insulin or thhe available insulin is blocked or inactivated by other substances thus preventing it from performing this function. This results in excess glucose in the blood. After a period of time this can lead to serious complications. The condition cannot be cured but can be controlled with lifelong treatment.

Type I and Type ll Diabetes

There are 2 types of diabetes:

Type lThis is also known as insulin dependent diabetes mellitus (IDDM). In Type l no insulin is made in the body. This can occur at any age but especially in the young. Treatment is in the form of dietary controls and insulin injections.

Type llThis is also known as non-insulin dependent diabetes mellitus (NIDDM). This accounts for 90% of all cases. In Type ll, the pancreas produces insufficient insulin. It usually occurs in people over the age of 40 and about 85% of patients are obese at the time of diagnosis. Very often other membes of their family also have diabetes. Type II diabetes can be treated by dietary controls alone or dietary controls and anti-diabetes tablet. Some may also need insulin injections.

Extra demands on the pancreas can also cause some women to develop diabetes during pregnancy. This is referred to as gestational diabetes (GDM). About 20-50% of GDM patients will develop diabetes in later life.

Diabetes Treatment

There is no cure for diabetes, but it can be controlled. The aim of diabetes treatment is to relieve the symptoms and return the blood sugar level to normal. Diabetes left uncontrolled can lead to long term damage to the kidneys, eyes, feet and blood vessels. The key to management of diabetes includes diet, exercise, anti-diabetes medication and insulin injections.

Diet

Diet plays a very important part in the management of diabetes. As diabetes is a disorder of glucose utilisation, many people assume incorrectly that they need only avoid sweet?foods and drinks to manage the condition. There's more to managing diabetes than that.

Diabetes should have 3 regular meals daily and they do not miss any meals.
Starchy foods which are high in fibre, should form the basis of a diabetic's diet. Such foods include wholemeal bread, noodles, oats, unsweetened crackers, chickpeas and lentils.
Foods that are high is sugar (e.g. white refined sugar, chocalate and honey) and fats should be kept to a minimum. Fat increases their risk of getting heart disease. It is also recommended that the food be grilled instead of fried.
Salty foods and salt intake must be reduced. Avoid foods such as crisps and peanuts.
Diabetics should plan their meals in advance. A consistent balance of?meals makes certain that there's a consistent intake of calories. This in turn ensures there's a consistent glucose load which the body can handle itself or with the help of anti-diabetes medications or insulin injections.
Adjustment of caloric intake is recommended to achievend maintain a desirable body weight.This can be done with the help of the doctor.
Alcohol consumption should be kept to minimum as too much alcohol can upset the blood sugar level.

Eating?'diabetic'? foods is not necessary as thet do not offer any special advantages for the diabetic patient. These products are noy usually any lower in calories than their ordinary counterparts. There are also specialised nutrition formulas for diabetics who can't stick to a diabetic diet. Such formulas aim to provide the nutritional requirements of the diabetic. It is important to remember that healthy eating is the key to a diabetic's diet and they can eat the same type of diet that everyone should be eating.

Exercise

Nearlyalf of patients withypeI diabetes are overweight. Their enlarged fat cells do not respond well to insulin and also require the body to produce more insulin. Besides dietary controls, exercise are great help in reducing weight. The goal is to keep their weights close to the ideal body weight. Regular exercise also helps the insulin to work better and keeps the patient healthier.

However, it is advisable for the patient to consult their doctor on a suitable exercise plan to avoid hypoglycaemia. This can happen if?the insulin does is not reduced before exercise or not enough food was consumed before exercise. Your doctor will be able to advice you on the choice of exercise, dietary and medication adjustments that may be required.

Insulin

Type I diabetic patient require insulin injecyions daily. Type II diabetic patientsmay or may not need them. The first insulin available for treatment was produced in 1921. During that time the insulin was extracted?from the?pancreas of cattle and pigs (bovine and porcine insulins). With the improvements in technology, synthetic human insulin, which is identical to the insulin made in our body, can now be produced using yeast and bacteria.

Insulin has to be given by injection as it can be destroyed in the stomach if taken orally. The patient's doctor makes decisions on insulin treatment, as each patient's insulin treatment is individualised according to the needs.

There are many types of insulin available.

The differrent types of insulin which are available are distinguished by:

the onset of action

the speed at which the injected insulin is absorbed into the blood

Peak

effect the time the insulin leveleaches its peak

Duration of action

the time it takes for the injected insulin to be absorbed.

Anti-Diabetes Tablets

These tablets do not contain insulin. Instead they contain drugs which either?help the pancreaso produce more insulin or help the body to use sugar more effectively. They can sometimes produce side effects like low blood sugar attacks, sickness, diarrhoea and rashes. Patients should notify?their doctor when?they experience unexpected problems after starting with these tablets.?

Diabetic Self-Care Needs

In addition to adhering to a strict regime of diet, exercise and medications, diabetics also have special self-care needs. Diabetic patients are prone to complications of the diseases, which cause long term damages. They have to protect themselves against these complications. Special care has to be taken of the skin, feet, eyes, and teeth to prevent infections and other problems cropping up.

Skin Care

Diabetics are prone to skin infections because the high sugar levels in the body are conducive to bacterial and fungal growth. As suach diabetics have to ensure that their skin care routine can minimise the occurence of skin infections. Therefore, correct skin cleansing and the use of skin care preparations are important.

Use cleasing agents which are acidic, with a pH of about 5.5. This ensures that the skin's natural protective function is maintained.
Cleansers should be mild, as strong preparations can irritate the skin.
Use lukewarm water to wash.
Alkaline-based cleansing agents should be avoided especially if the skin is itchy or inflamed.
Refrain from scratching if skin is itchy. A break in the skin can encourage infection. Apply a lotion or cream with anti-itch properties.
When washing do not forget areas such as armpits, genital and perianal areas, skin folds on the areas between the toes.
After washing, apply a moisturising lotion to keep the skin moist and supple.
Take special care to avoid any injuries or scratches.

Foot Care

Foot care is especially important to the diabetic patient. In addition to skin infections, the feet are also prone to ulceration. This is due to the reduced blood supply and oxygen to the legs.

Diabetics should wash their feet daily and dry them thoroughly. Remember to ensure that the spaces between the toes are kept dry too.
If you have dry skin, massage a little moisturising cream onto it, but not between the toes.
Socks are to be changed daily.
Toenails should be kept trimmed. When trimming toenails do it straight across and avoid trimming too close to the skin to avoid unnecessary injuries.
Shoes should be comfortable and not too tight a fit. Always feel inside shoes before putting them on as the reduced sensitivity in the feet prevents you from feeling sharp pbjects or pieces of grit under the feet.
The feet must be examined daily to look out for scratches, blisters, ulcers or any other wounds.
Diabetes should not go around barefoot.
It is important to remember not to apply any chemical agents to the feets such as corn or callous removers including corn plasters. These contain acids, which can be very dangerous to the diabetic patient.

Eye Care

Diabetics are also prone to certain eye diseases such as cataracts, glaucoma and even blindness (due to retinopathy). The incidence of cataracts is higher in diabetes and also it progresses at a faster rate in diabetics.

Glaucoma is also more common in diabetics. Early diagnosis and proper management is essential to prevent optic nerve damage and loss of vision as a consequence of the damage.

Diabetic retinopathy is one of the leading causes of blindness. The longer the person suffers from diabetes, the greater the risk of developing diabetic retinopathy which can lead to blindness.

Diabetic must:

go for annual eye check-ups.
carry out blood pressure checks routinely.
refer to an ophthalmologist promptly if there are visual problems.

Tooth Care

Care on the teeth is also important. Diabetics should be careful of any lesions in the mouth or gums. These can easily become infected and cause a myriad of problems.
Diabetics shouls pay a 6 monthly visit to their dentist to ensure that all is well with their gums and teeth.

Technorati Tag: Diabetes Diabetic Malaysia food supplement

Genome Canada gives additional investment of C$59 million in Ontario genomics research

2007-03-20T19:29:00.000-07:00

Maurizio Bevilacqua, Secretary of State (Science, Research & Development) on behalf of Allan Rock, Minister of Industry, Dr. Martin Godbout, President and CEO of Genome Canada, and Ronnie Gavsie, President of Ontario Genomics Institute, announced the approval of thirteen new genomics research projects worth $118 million, $59 million of which will be provided by Genome Canada in 2002. The announcement was made at the Hospital for Sick Children where groundbreaking research on cystic fibrosis and diabetes will take place as a result of the announcement.

1. Proteomics and Functional Genomics: An Integrated Approach
Total Project Cost $15,000,000
Genome Canada Contribution $7,500,000
Project Leaders: Brenda Andrews and Cheryl Arrowsmith

2. Viral Proteomics
Total Project Cost $10,486,066
Genome Canada Contribution $5,243,033
Project Leaders: James Guohua Pan and Don Awrey

3. Functional Genomics of Arabidopsis
Total Project Cost $1,628,546
Genome Canada Contribution $814,273
Project Leader: John Coleman

4. Functional Genomics of Type 1 Diabetes
Total Project Cost $10,870,128
Genome Canada Contribution $5,435,064
Project Leader: Jayne Danska

Type 1 diabetes is a growing, world-wide health problem for which there is no known cure. This project is focused on understanding the root causes of Type 1 diabetes, in particular, the genetic basis, which makes people susceptible. To date, the ability to understand Type 1 diabetes, or indeed, many other similar diseases such as rheumatoid arthritis and multiple sclerosis, has been hampered by our understanding of two variables: the genes contributing to the disease and the biological pathways which these genes control. Ongoing research with rodent models of Type 1 diabetes have identified genetic regions involved in the early stages of Type 1 diabetes. The researchers believe that the genes involved in the disease pathways in rodents are likely to be similar in humans. Genes identified in the rodent studies will be used as candidate genes for study in humans with Type 1 diabetes. The investigators will study three well-characterized populations: 1) families from Newfoundland (where there is one of the highest rates of Type 1 diabetes in the world); 2) families of French origin in Quebec; and 3) families from a large North American clinical trial of Type 1 diabetics. This genome-wide integration of rodent and human Type 1 diabetes studies is aimed at identifying the genetic pathways that make people susceptible to this disease. This project is a collaboration among the Hospital for Sick Children, Sunnybrook and Women's College Health Science Centre, McGill University Health Center (Montreal Children's Hospital) and Memorial University of Newfoundland.

5. Genomic Analyses of Soil Microorganisms
Total Project Cost $5,862,145
Genome Canada Contribution $2,931,073
Project Leaders: Turlough Finan and Brian Golding

6. The Biomolecular Interaction Network Database (BIND)
Total Project Cost $25,000,000
Genome Canada Contribution $12,500,000
Project Leader: Christopher Hogue

7. Mapping and Isolation of Genes Influencing Severity of Disease in Cystic Fibrosis
Total Project Cost $6,728,404
Genome Canada Contribution $ 3,364,202
Project Leader: Lap-Chee Tsui

8. Fiber Optic Nucleic Acid Biosensor Based Gene Profiling: Proof of Principle by Screening for Drug Leads for Orphan Neurodegenerative Disorders and SNP Analysis
Total Project Cost $3,000,000
Genome Canada Contribution $1,500,000
Project Leader: Alex MacKenzie

9. Genomics of the Spruce Budworm and its Viral Pathogens
Total Project Cost $4,653,298
Genome Canada Contribution $2,326,649
Project Leader: Arthur Retnakaran

10. The Stem Cell Genomics Project
Total Project Cost $11,133,406
Genome Canada Contribution $5,566,703
Project Leader: Michael Rudnicki

11. Genetic Determinants of Human Health and Disease
Total Project Cost $11,697,564
Genome Canada Contribution $5,848,782
Project Leader: Katherine Siminovitch

12. Bridging the Emerging Genomics Divide
Total Project Cost $2,830,006
Genome Canada Contribution $1,415,003
Project Leader: Peter Singer

13. Development and Applications of Functional Genomics Technologies
Total Project Cost $8,171,670
Genome Canada Contribution $4,435,835
Project Leader: James Woodgett

Technorati Tag: Diabetes Diabetic Malaysia food supplement

Walk Away from Diabetes

2007-03-19T00:23:00.000-07:00

Young couch potatoes have more to worry about than just their weight. New research shows that watching TV and not getting exercise increase children's risk of later developing type 2 diabetes, as well as heart disease and other conditions.

Type 2 diabetes is a burgeoning health problem in America and around the globe. It was once found almost exclusively in older adults, but studies are showing an alarming trend of younger people developing type 2 diabetes.

Physical activity also makes diabetes pills and insulin therapy work better in controlling blood sugar.

U.S. health agencies say that 176,000 American kids and 20.6 million adults now have type 2 diabetes - and that more than a third of Americans born in 2000 will become diabetic. Meanwhile, a large European study found that lack of exercise and excessive amounts of television watching were each risk factors for type 2 diabetes in 9-year-olds.

Although exercise can help prevent diabetes from occurring in the first place, it is also an important part of controlling diabetes once the disorder has been diagnosed. Exercise is one of the three main tools (along with diet and medication) that doctors recommend to manage diabetes. Exercise lowers blood sugar, insulin, blood fats and blood pressure. It also helps diet and medication work better and has many other health benefits.

The amount and type of exercise a person needs varies. The American Diabetes Association (ADA) recommends that people with type 2 diabetes get plenty of aerobic exercise such as walking or bike riding - at least 150 minutes a week at moderate intensity or at least 90 minutes a week at vigorous intensity, spread over at least three days.

The ADA also recommends strength training three days a week. But remember to talk with a doctor before starting or changing an exercise program.

A doctor can tell you which exercises are best for you, which you might need to avoid, at what level you should start and how fast you may progress. Then you'll be able to enjoy the many benefits of exercise, including:
- Lower blood sugar and better control of diabetes
- Weight loss
- Better control of high blood pressure
- Improved cholesterol levels
- Better cardiovascular health
- Lower risk of diabetic kidney disease, foot problems, eye conditions, nerve damage, sexual dysfunction and other problems
- Less stress and improved mood

Exercise can work hand in hand with other treatments for diabetes. For instance, loss of excess weight is usually easier through the combination of physical activity and a sensible diet than through only one of these methods. Diabetic patients who regularly exercise are often allowed greater choices and more leeway in their diet. Physical activity also makes diabetes pills and insulin therapy work better in controlling blood sugar.

Excerpt from ERA Consumer.org

Technorati Tag: Diabetes Diabetic Malaysia food supplement

Senaman bantu pesakit diabetes

2007-03-18T16:28:00.000-07:00

SANA-SINI orang bercakap mengenai kepentingan bersenam dan rasanya semua orang tahu manfaat yang diperoleh daripada pergerakan badan itu. Soal pengurusan kesihatan memang boleh menjadi perkara remeh dan payah jika tiada kesungguhan.

Memang perkara ini berulang kali dibincangkan, tetapi masih ramai tidak tahu keperluan asas sebelum bersenam. Menurut buku panduan yang diterbitkan Unit Pemakanan, Bahagian Kesihatan Awam, Jabatan Kesihatan Wilayah Persekutuan Kuala Lumpur, beberapa persediaan perlu diambil kira.

Paling penting ialah meminta nasihat doktor jika anda berusia 35 tahun dan tidak biasa bersenam, mempunyai masalah kesihatan dan mengalami masalah berat badan berlebihan (sebanyak 20 peratus lebih daripada berat badan unggul).

Bukan mudah untuk membakar kalori yang dimasukkan ke dalam badan. Sekeping roti canai mengandungi 300 kalori memerlukan sekurang-kurangnya 120 minit berjalan (lelaki) atau 86 minit (perempuan) untuk dibakar.

Sepinggan mi goreng (859 kalori) memerlukan seseorang lelaki berlari 88 minit atau 64 minit bagi perempuan untuk membakar kalori tadi.

Namun inilah realitinya. Jadi, ini sebabnya kita perlu bijak menseimbangkan antara pengambilan makanan dan aktiviti harian supaya tidak timbul masalah berlebihan berat badan.

Lebih parah jika berat badan berlebihan turut dikaitkan dengan masalah kesihatan seperti tekanan darah tinggi, kolesterol tinggi dan kencing manis.

Dalam ghairah untuk memulakan lembaran baru dalam hidup, beberapa peraturan mesti dipatuhi, iaitu jangan bersenam apabila:

Badan terasa tidak sihat
Berasa sakit sendi dan kaki
Sejurus selepas makan (mesti berehat sekurang-kurangnya dua jam)
Apabila cuaca terlalu panas
Mandi air panas sejurus selepas bersenam

Ada pendapat mengatakan, bersenam hanya memberi manfaat kepada badan jika ia mampu meningkatkan kadar degupan jantung atau nadi kepada 120 hingga 150 denyutan seminit. Tidak kira apa senaman dipilih, pastikan ia selamat dan dilakukan mengikut kemampuan anda.

Baik bagi orang yang sihat atau mempunyai penyakit, asasnya adalah sama iaitu kesederhanaan. Senaman boleh dibahagikan kepada beberapa jenis iaitu senaman regangan, aerobik dan rintangan.

Contoh senaman regangan adalah seperti yang dilakukan setiap kali sebelum senaman dimulakan. Senaman regangan mudah adalah seperti meregangkan leher (mengiringkan kepala ke kanan atau kini beberapa saat), bahu (menarik tangan kanan ke arah kiri sambil tangan kiri mengampu di bawah siku kanan), betis dan paha.

Senaman aerobik pula lebih cergas sifatnya seperti berbasikal, berjalan, berjoging, berenang dan menari.

Senaman rintangan pula bertujuan menguatkan anggota tertentu seperti duduk di kerusi sambil mengangkat kaki ke paras kerusi atau mengangkat dumbel.

Pengurus Fisioterapi Institut Jantung Negara, Datin Maimunah Johari, berkata pesakit diabetes perlu menjalani kehidupan aktif dan bersenam setiap hari sekurang-kurangnya selama 30 minit yang mesti dijadikan rutin harian.

Ia penting untuk menurun dan mengawal paras gula dalam darah. Namun, perkara ini jarang diberikan perhatian oleh kebanyakan pesakit. Tahap senaman pula perlu sesuai dengan umur pesakit.

Bagi pesakit muda dan mengalami masalah berat badan, Maimunah menyarankan supaya bersenam selama sejam setiap hari. Manakala bagi pesakit diabetes yang mempunyai berat badan normal, bersenam 30 minit sehari memadai.

“Pesakit yang bekerja di pejabat juga perlu berusaha untuk bergerak aktif dengan banyak berjalan dan bangun ketika menjawab panggilan telefon. Apabila balik ke rumah, cari peluang untuk berjalan keliling kawasan perumahan sebelum diikuti dengan aktiviti senaman.

“Pesakit juga mesti mematuhi jadual pengambilan ubat. Jangan makan ubat dengan perut kosong kerana jika pesakit bersenam pada hari itu ia boleh menimbulkan masalah hipoglisemia.
Pesakit boleh pitam ketika bersenam,” katanya.

Sementara itu, pesakit berumur melebihi 60 tahun dan sudah lama menghidap diabetes pula perlu memeriksa kaki setiap kali sebelum memakai kasut dan masuk tidur.

Ini kerana kebanyakan pesakit diabetes tua mengalami masalah kemerosotan otot dan deria sentuh menjadi kurang sensitif.

Masalah ini menyebabkan mereka tidak sedar kaki melecet (akibat kasut ketat) dan luka itu bukan saja lambat sembuh, tetapi mudah melarat jika tidak diberikan rawatan rapi. Ini juga sebabnya ramai pesakit diabetes terpaksa dipotong kaki.

Malah, mereka juga disaran supaya membawa teman, sama ada ahli keluarga atau jiran, ketika melakukan senaman untuk mengelakkan kemungkinan tidak diingini.

Bagi golongan yang dikategorikan sebagai ‘atas pagar’ (paras gula dalam darah agak tinggi, tetapi belum dikategorikan sebagai pesakit kencing manis) dan mempunyai sejarah keluarga mengalami masalah kegagalan buah pinggang dan kencing manis, risiko penyakit boleh direndahkan dengan bersenam dan pada masa sama paras gula boleh dikurangkan tanpa perlu mengambil ubat.

Dalam risalah terbitan Perkhidmatan Fisioterapi Kementerian Kesihatan menggariskan beberapa perkara untuk pesakit diabetes, iaitu:

Mendapatkan nasihat doktor
Memakai kasut yang sesuai
Minum air segelas
Bersenam selepas satu atau dua jam selepas makan
Bersenam sekurang-kurangnya 30 minit selepas suntikan insulin

Bawa bekalan air dan gula-gula (langkah berjaga-jaga jika berlaku ada tanda hipoglisemia)
Jangan bersenam pada lewat petang atau badan berasa tidak sihatSenaman mestilah dimulakan secara berperingkat mengikut turutan betul dan disertakan dengan aktiviti regangan bagi mengelak kecederaan otot dan sendi. Anda mesti berhenti bersenam jika mengalami tanda:

Lemah anggota
Menggeletar
Pening
Banyak berpeluh (berlebihan)
Penglihatan menjadi kabur
Rasa berdebar-debar
Lapar
Berasa terlalu letih

Selepas bersenam, jangan terus duduk, sebaliknya berjalan perlahan-lahan untuk menyejukkan badan. Ketika ini pesakit juga tidak digalakkan terus mandi, sebaliknya minum air secukupnya bagi menggantikan air yang hilang melalui peluh ketika bersenam.

Ketika berehat di rumah, pesakit diabetes masih boleh melakukan senaman kaki ringan, iaitu dengan memusingkan pergelangan kaki mengikut putaran jam dan sebaliknya. Buat beberapa kali dan ulang jumlah sama untuk kaki sebelah lagi.

Selepas itu, gerakkan jari kaki ke atas dan bawah. Buat sekurang-kurangnya 10 kali untuk setiap arah. Senaman ini boleh dilakukan sambil duduk atau baring.

Kemudian, berdiri dan angkat tumit. Jika mampu boleh buat serentak untuk kedua-dua belah kaki tetapi jika tidak, buat sebelah kaki dulu. Jika anda mengalami ulser atau luka pada kaki, jangan lakukan senaman berat. Memadai jika mengayuh basikal saja.

Mengapa perlu bersenam? Bersenam bukan saja dapat menyihatkan, menjaga berat badan dan melancarkan aliran darah, tetapi yang lebih penting bagi pesakit diabetes ialah ia mampu meningkatkan kadar penyerapan insulin dan mengawal paras gula dalam darah.

Dari Harian Metro
Oleh NORLAILA HAMIMA JAMALUDDIN
norlaila@hmetro.com.my

Link: Tak jaga makan punca diabetes

Diabetes menjejaskan kesihatan seksual

2007-03-16T20:23:00.000-07:00

Dari Utusan Online

SOALAN: Saya berusia lewat 40-an dan menghidap diabetes sejak 10 tahun yang lalu. Namun sejak kebelakangan ini, saya merasakan hubungan intim dengan isteri tidak lagi sehangat dulu.
Ini kerana saya sukar untuk mencapai dan mengekalkan ereksi. Adakah ia berkaitan dengan diabetes yang saya alami? Apakah ia masih boleh diatasi? Tolong jelaskan.

Jawapan
Diabetes merupakan antara masalah kesihatan utama yang menjejaskan kesihatan seksual lelaki. Semakin lama seseorang itu menghidap diabetes, maka semakin tinggi risiko untuk mendapat disfungsi erektil.

Ada kajian menjangkakan mereka yang menghidap diabetes yang tidak terkawal berisiko mengalami disfungsi erektil sehingga 10 tahun lebih awal berbanding dengan mereka yang normal.

Peratusan pesakit diabetes yang mengalami mati pucuk adalah empat kali ganda lebih tinggi berbanding lelaki biasa. Ini kerana mereka yang mengalami diabetes cenderung untuk mengalami kerosakan saraf.

Kerosakan saraf ini akan turut menjejaskan pengaliran darah ke bahagian anggota badan termasuk alat kelamin lelaki yang akan menjejaskan keupayaan ereksi yang baik.

Tambahan pula ubat-ubatan yang diambil turut menyumbang kepada masalah ini.

Terdapat juga kajian yang merumuskan wanita yang menghidap diabetes berhadapan dengan risiko yang lebih besar berbanding lelaki.

Bagi mereka yang sedang mengalami kemerosotan kesihatan seksual seperti keinginan seks yang menurun atau masalah ereksi, pengambilan ginseng boleh membantu meningkatkan aliran darah sekali gus menggalakkan ereksi.

Ia juga berperanan untuk meningkatkan tenaga batin. Gingko pula mengendurkan saluran darah dan meningkatkan aliran darah ke bahagian alat kelamin.

Herba-herba lain yang didapati membantu menggalakkan keinginan seksual dan prestasi seksual termasuklah Muira puama, Puncture vine, Withania dan Damiana.

Herba dan kajian klinikal

SOALAN: Saya sudah berumah tangga sejak 15 tahun yang lalu. Kini suami saya berumur 55 tahun dan saya pula 45 tahun. Secara umumnya kami tidak mempunyai masalah dari segi hubungan intim.

Walau bagaimanapun, dia begitu percaya kepada herba tradisional yang dikatakan dapat meningkatkan tenaga batin. Pada pendapat saya, segalanya ada kaitan dengan cara kita berfikir.
Namun, dia mempercayai herba itu boleh membantu. Soalan saya, adakah herba tersebut benar-benar bermanfaat dalam mengekalkan kesihatan seksual?

Jawapan

Hubungan intim suami isteri bukan hanya bergantung kepada kesihatan fizikal, malah ia juga dipengaruhi oleh pelbagai faktor.

Hubungan intimasi memerlukan penumpuan atau kerjasama fizikal dan emosi. Contohnya seseorang itu akan menjadi dingin dalam seks apabila dia stres.

Begitu juga dengan lain-lain masalah kesihatan seperti diabetes dan tekanan emosi yang turut mengakibatkan kelemahan dalam keinginan seks serta menyukarkan ereksi di kalangan lelaki.
Kadangkala, keberkesanan suplemen atau ubat yang diambil lebih dipengaruhi oleh pemikiran berbanding tindak balas fisiologi/tubuh.

Memandangkan herba telah mendapat tempat dalam perubatan tradisional khususnya untuk kesihatan seksual sejak berabad lamanya, kini ia turut mendapat perhatian para penyelidik untuk mengkaji keberkesanan herba-herba terpilih secara klinikal.

Contoh herba-herba yang didapati berkesan untuk meningkatkan fungsi seksual termasuklah Horny goat weed, ginseng, ginkgo, Puncture vine, Muira puama, Withania dan Damiana.

Setiap jenis herba ini memiliki mekanisme atau fungsi yang unik dalam meningkatkan kesihatan seksual.

Horny goat weed merupakan sejenis herba tradisional dari China yang telah digunakan untuk mengatasi masalah mati pucuk sejak dua ribu tahun dahulu.

Kajian klinikal telah membuktikan bahawa Horny goat weed yang diambil sebanyak 800mg sehari memberi kesan positif pada kesihatan seksual dan sistem pertahanan badan pesakit.

Bagi kaum lelaki, Horny goat weed memberi kesan yang menyerupai testosteron (hormon seks lelaki), meningkatkan keinginan terhadap aktiviti seks dengan meningkatkan penghasilan sperma dan merangsang kepekaan sistem saraf.

Bagi kaum wanita pula, ia membantu melegakan simptom menopaus seperti kemurungan serta kurang minat terhadap seks.

Sekiranya seseorang memilih formulasi herba untuk mengekalkan kesihatan seksual, pastikan dos pengambilan dan keberkesanannya telah terbukti secara klinikal. Pada masa yang sama, ia seharusnya diambil mengikut saranan yang ditetapkan.

Dari DiabetesMilkPowder.com :

GTF boleh meningkatkan kemampuan seks

INTERNATIONAL DIABETES FEDERATION: DIABETES AND CARDIOVASCULAR DISEASE TIME BOMB

2007-03-14T19:16:00.000-07:00

The global diabetes epidemic is set to contribute to an explosion of cardiovascular disease, warns the publication of the International Diabetes Federation (IDF)in 2001, launched today at the annual meeting of the European Association for the Study of Diabetes in 2001.

Because of the rising prevalence of diabetes worldwide, it now ranks alongside smoking, high blood pressure and cholesterol disorders as a major risk factor for cardiovascular disease.

In fact, the 150 million people around the world who already have diabetes are two to four times more likely to develop cardiovascular diseases such as heart attack or stroke than people without diabetes.

"When we consider that the number of people with diabetes around the world is predicted to double over the next 25 years, the outlook for cardiovascular disease becomes even more alarming", said Professor Sir George Alberti, President of the IDF.

Diabetes and Cardiovascular Disease: Time to Act is the most up-to-date global report on the two diseases, and contains the latest mortality data for coronary heart disease and cerebrovascular disease in over 100 countries.

The publication cautions that the recent decline in cardiovascular disease witnessed in the USA, Australasia and Western Europe may be compromised significantly by the upsurge in diabetes.

In other parts of the world, like Eastern Europe and the former Soviet Union, where cardiovascular disease has been proliferating in recent years, the additional impact of diabetes threatens to have devastating consequences.

"If urgent action is not taken to defuse the situation, a global explosion of cardiovascular disease is just waiting to happen", added Professor Alberti.

One of the key messages spelt out in the publication is the importance of prevention: both of diabetes in the first place and, when diabetes is present, of cardiovascular risk factors in people with the condition. The good news is that these dual objectives can be achieved by common lifestyle strategies, such as diet and physical activity.

However, Bjornar Allgot, IDF Vice President and himself a person with diabetes, stressed that leading a healthy lifestyle is not only an individual responsibility. "We are living in a hostile society, where even exercising can be difficult, expensive and dangerous. The worse thing we can do is impose guilt on people who already have a difficult disease to live with."

"Governments can and must contribute to the battle against this double scourge by encouraging and facilitating lifestyle changes, providing health education for all and investing in primary prevention programmes", challenged Professor Alberti. "There can be no doubt that now is the time to act."

Diabetes and Cardiovascular Disease: Time to Act, sponsored by an educational grant from Merck, Sharp & Dohme, is available in English, French and Spanish.

SOURCE : International Diabetes Federation
WEB SITE : HTTP://WWW.IDF.ORG

Technorati Tag: Biotechnology pharmaceutical Diabetes Diabetic Malaysia food supplement Health & wellness

Tak jaga makan punca diabetes

2007-03-13T19:08:00.000-07:00

SETIAP kali melihat diri di cermin, pernahkah terfikir corak kehidupan bagaimana yang mahu anda lalui sehingga akhir hayat nanti? Memang tiada siapa dapat meramalkan apa bakal terjadi esok mahupun sekejap lagi, tetapi banyak perkara boleh dilakukan untuk persediaan hidup masa depan, termasuk kesihatan.

Baik yang masih sihat atau menghidap penyakit tertentu, soalan ini sama pentingnya. Tidak kira apa cara bakal digunakan, tujuannya masih sama, iaitu supaya dapat menikmati hari tua dalam keadaan sejahtera.

Justeru, antara langkah pertama yang perlu diambil ialah melakukan perubahan gaya hidup dan ia hendaklah dimulakan hari ini juga. Persoalannya, adakah kita benar-benar mahu berubah? Jika mahu, apa yang mahu, boleh dan sanggup lakukan? Apa pula perkara yang tidak sanggup dilakukan?

Ketua Perkhidmatan Endokrinologi, Diabetologi dan Obesiti, Hospital Universiti Geneva, Profesor Alain Golay, berkata jawapan pada persoalan inilah yang akan menentukan status kesihatan kita pada masa depan kerana penjagaan kesihatan adalah tanggungjawab sendiri.

Tanggungjawab ini lebih berat bagi orang yang menghidap penyakit kronik seperti kencing manis. Kencing manis bukan lagi penyakit orang tua kerana kini ramai golongan muda diserang kencing manis, walaupun umur baru menjangkau 30 tahun, disebabkan kurang kesedaran menjaga pemakanan.

Kebanyakan kes kencing manis yang dilaporkan di negara ini berpunca daripada berlebihan nutrien (akibat terlalu banyak makan makanan berkalori tinggi) dan obesiti, terutama di kalangan kumpulan berisiko seperti individu obes, mempunyai ahli keluarga yang menghidap kencing manis dan mengalami masalah tidak toleran glukos.

Namun orang, termasuk golongan berisiko tinggi ini, menganggap mereka tidak akan diserang penyakit dan ia hanya berlaku pada orang lain. Ini sebabnya apabila disahkan menghidap penyakit tertentu, mereka sukar menerima hakikat berkenaan dan mula mengalami pelbagai gangguan emosi.

Katanya, menghidap penyakit bukan bererti kehidupan kita berakhir. Pengamal perubatan dan pesakit perlu melihatnya daripada sudut positif kerana selama ini ramai hanya memandang penyakit daripada sudut negatif sehingga melemahkan semangat.

“Bagi pesakit, sikap positif ini boleh dipupuk dengan mempelajari mengenai penyakit dan mengambil bahagian dalam merancang atau menentukan kaedah rawatan yang sesuai dengan gaya hidup anda. Pengamal perubatan pula mestilah belajar kemahiran baru dengan memerhatikan emosi, keupayaan dan harga diri pesakit.

“Ini kerana pesakit biasanya mengalami pelbagai masalah pemakanan seperti diet pelbagai, diet yo-yo, tabiat suka mengunyah, menjadikan makanan untuk meredakan gangguan emosi atau sentiasa berasa dia perlu mengehadkan pengambilan makanan,” katanya.

Beliau berkata demikian ketika simposium kesihatan Mengawal Paras Glukosa Darah dan pelancaran snek Nutren Balance yang direka khusus untuk pesakit kencing manis anjuran bersama Persatuan Pengamal Perubatan Swasta Selangor dan Kuala Lumpur dan Nestle (Malaysia) Berhad.

Masalah akan lebih buruk jika pesakit diabetes menjadikan makanan sebagai cara atau rangsangan untuk melegakan perasaan, sama ada ketika berasa tertekan, letih, bosan, resah dan mempunyai masalah.

Rangsangan ini boleh timbul dengan hanya melihat makanan, ketika lapar, menyediakan makanan atau membeli-belah.

Di sinilah pentingnya pesakit perlu berbincang dengan doktor untuk mengatasi masalah mereka kerana kaedah rawatan untuk setiap pesakit berbeza. Malah pesakit perlu merancang strategi bagi mengatasi masalah keinginan untuk makan.Antara strategi yang disarankan Dr Golay ialah:

Sentiasa ingat untuk menjaga kesihatan diri
Melakukan aktiviti fizikal
Berehat dan menarik nafas panjang-panjang
Membuat panggilan telefon
Berjalan-jalan
Mandi

Namun, katanya, rawatan kognitif paling berkesan ialah bersenam dan cuba mengawal pengambilan makanan. Keinginan untuk makan boleh diperbaiki dengan snek berkhasiat (rendah lemak).

Malah, pesakit kencing manis juga perlu bijak memilih makanan untuk mengawal paras glukos dalam darah.

Justeru, pesakit disaran mengambil makanan yang mempunyai indeks glisemik rendah seperti buah-buahan, kekacang dan sayur-sayuran serta kurangkan makanan berkarbohidrat dan berlemak (seperti roti, kek mahupun manisan) kerana ia mempunyai indeks glisemik tinggi.

Ini kerana makanan yang mempunyai indeks glisemik tinggi memerlukan lebih banyak insulin, sedangkan pesakit kencing manis jenis 2 tidak mampu menghasilkan cukup insulin bagi menggunakan glukos berkenaan. Akibatnya, paras gula dalam darah meningkat (hiperglisemia) dan boleh mendatangkan komplikasi kepada pesakit.

Pun begitu, cara lebih baik ialah mengawal pemakanan sejak awal supaya penyakit dapat dihindarkan, kata Perunding Endokrinologi, Datuk Dr Khalid Kadir. Ia perlu dijadikan keutamaan dalam hidup, khususnya bagi individu berisiko tinggi.

“Diabetes adalah titik akhir bagi Sindrom Metabolik. Kebanyakan masalah diabetes boleh dikawal pada peringkat diagnosis lagi, iaitu apabila menjalani pemeriksaan paras glukos darah melalui pemakanan dan senaman. Individu yang mengalami masalah obesiti perlu menurunkan berat badan dan kurangkan makanan berlemak serta berkolesterol tinggi.

“Pesakit kencing manis yang ada masalah jantung mesti mengurangkan makanan bergaram, bersos atau banyak bahan pengawet. Pada masa sama, pesakit perlu memastikan mereka mendapat cukup kalsium. Semua ini perlu dilakukan sebaik mendapati paras glukos anda tinggi dan jangan tunggu hingga disahkan mendapat diabetes,” katanya.

Mengapa pengamal perubatan memberi penekanan kepada kawalan makanan? Menurut Dr Khalid, diabetes tidak terkawal akan menyebabkan banyak komplikasi kesihatan, termasuk buta, degup jantung tidak normal dan kehilangan sensitiviti deria sentuh, terutama pada kaki.

Kawalan diabetes akan lebih berkesan jika pesakit menjaga makan dan kerap bersenam.

Kajian di China menunjukkan, perkembangan penyakit dapat dikurangkan kepada 31 peratus melalui diet saja, 42 peratus melalui senaman saja dan 46 peratus melalui diet serta senaman.

Malah, pesakit juga dinasihatkan makan sedikit tetapi kerap kerana ia akan mengurangkan keperluan insulin.

Namun lebih baik jika kawalan makanan dapat dilakukan sejak awal supaya kita masih dapat menikmati makanan kegemaran, termasuk yang berlemak dan berkalori tinggi, apabila tua kelak.

Dari Harian Metro

Link: Senaman bantu pesakit diabetes

Global Walk to Cure Diabetes

2007-03-13T05:39:00.000-07:00

Ford Malaysia has drawn the battle lines in the fight against diabetes. In 2004, staff joined hands to organize the first Ford Motor Company Global Walk to Cure Diabetes in Malaysia, the aim of this charity walk was to create awareness as well as raise funds for diabetes.

The result was a resounding success, raising a total of RM42,586.30 from Ford Malaysia staff, business partners, suppliers and corporate sponsors. The first event saw over 200 Ford Malaysia employees and their families take part in a symbolic 2.7km walk in Taman Pertanian Bukit Cahaya Seri Alam on December 19, 2004.

The following year the team raised RM69,743.46 and grew this event to reach out to its dealerships and business partners.

All funds raised are divided accordingly and channeled to the following organisations to help them in the fight against diabetes:

25% to Persatuan Diabetes Malaysia - is the first national diabetes non-governmental organisation be established and has multiple branches throughout the country. It organises counseling sessions, public forums, talks and diabetes education conferences for health care professionals and the general public.

25% to Division of Pediatric Endocrinology, Department of Pediatrics, Universiti Malaya Medical Centre - cares for children with diabetes and is also involved in diabetes and obesity research.
50% to Juvenile Diabetes Research Foundation International (JDRF) - the leading charitable funder and advocate of Type 1 (juvenile) diabetes research worldwide. The mission of JDRF is to find a cure for diabetes and its complications through the support of research. For more information visit www.jdrf.org

Type 1 Diabetes is a disease which strikes children suddenly and requires multiple injections of insulin daily or a continuous infusion of insulin through a pump. Insulin, however, is not a cure for diabetes, nor does it prevent its eventual and devastating complications which may include kidney failure, blindness, heart disease, stroke, and amputation.

The Global Walk to Cure Diabetes organised in Malaysia is part of a global effort at Ford facilities around the world with the aim of raising awareness and funds for diabetes research.

Ford Malaysia was the first Ford facility in Asia to participate in the world-wide initiative and has made it a yearly event.

Diabetes is a major health concern worldwide. According to the World Health Organisation, at least 171 million people worldwide have diabetes. This figure is likely to more than double by 2030 to reach 366 million.

In Malaysia, it is estimated that 8% of the population has diabetes. As such efforts to create awareness of diabetes is critical and especially to reach out to risk groups and equip them with the knowledge and support to fight back.

Donations for the local event were generated through a number of ways including donations in cash and kind from Ford suppliers, business partners and corporate sponsors as well as various fund raising activities at the Ford plant in Shah Alam such as the sale of cakes and cookies, tyres and rims, and toys.

Some of the key sponsors include Taman Pertanian Malaysia Bukit Cahaya Seri Alam, Deromp Marketing, Nestle MILO, Sime Oleander, Gardenia, Persatuan Diabetes Malaysia, Abbott as well as Ford Malaysia's business partners and suppliers.

How you can support this initiative:
There are a number of ways that you can do this:
Cash Donation - Cheques should be made out to, "Ford Malaysia Sdn. Bhd." and marked at the back, "Global Walk to Cure Diabetes".
Donations of items in kind - that will be sold to staff and the money raised channeled to this fund
*Collect donations from family and friends and join us for the Global Walk to Cure Diabetes event in November 2006 Sponsorship of food, beverages, goody bag items or prizes for the Global Walk to Cure Diabetes event

2006-Classic cars for diabetes awareness do

IF you are into classic cars and keen to do your part for diabetes prevention awareness, why not participate in the Global Walk to Cure Diabetes at Taman Pertanian Malaysia Bukit Cahaya Seri Alam in Shah Alam.

The highlights of year 2006 event include a display of about 30 vintage classic and modern classic cars at Taman Pertanian with the support of the Malaysia and Singapore Vintage Car Register (Central Region).

Among the vehicles expected to be on display would be a Ford Tudor 1931, Ford Capri 315 two-door coupe 1963, Ford Capri 315 four-door 1963, Ford 1100, Ford Cortina 1600 1974, Ford Escort and Ford Grenada.

Also expected are a Volvo P 1800 1970, Volvo 122, Volvo 121 station wagon 1965, Mini Countryman, Mini Mork, Alfa Voloce 1.6GT 1967, Opel Manta 1967, Datsun Fairlady 1963, Triumph TR3A 1964, Jaguar Mark 2 1964, Cadillac Coupe DeVille 1959, Volkswagen 1968 and Passat Miura 1980.

Ford Malaysia Sdn Bhd with the support of its suppliers and business partners has raised over RM50,000 this year. Ford Malaysia was the first Ford facility in Asia to participate in this initiative in 2004.

This event is organised by Ford facilities around the world with the objective of raising awareness and funds for diabetes research.

Over the past two years, Ford Malaysia has raised over RM100,000 towards this cause.
"This event allows our staff, suppliers and business partners to join hands and make a difference. Our hope is that the awareness created through this event will equip us with the knowledge and financial resource in the fight against diabetes," said Lindsay Benson, organising chairperson of the Global Walk Team 2006.

The Global Walk is a family-day type event that is expected to attract over 300 participants.
The event will start off with a symbolic 2.7km walk in Taman Pertanian that will be followed by light breakfast and other activities for adults and children.

There will be a special talk by Persatuan Diabetes Malaysia and a free blood glucose test as well as a magic show, balloon sculpting, face painting and sand art activities for the kids.

Donations for the local event were generated through a number of ways including donations in cash and kind from Ford suppliers and business partners.

Other fund-raising activities included a jumble sale, sale of event T-Shirts, breakfast, toys and donated items in-kind were also held at the Ford plant in Shah Alam over the last few months.
The sponsors for the event this year include Taman Pertanian Malaysia Bukit Cahaya Seri Alam, Nestle MILO, Eau Claire Mineral Water, Gardenia and Deromp Marketing.

About 50% of the funds raised for the event will be divided equally between Persatuan Diabetes Malaysia and the Division of Pediatric Endocrinology, Department of Pediatrics, Universiti Malaya Medical Centre, to help them in the fight against diabetes.

The remaining 50% will be handed over to the Juvenile Diabetes Research Foundation International (JDRF), the largest charitable funder of diabetes research in the world.

Technorati Tag: Biotechnology pharmaceutical Diabetes Diabetic Malaysia food supplement Health & wellness

Institute announces diabetes-related research advance

2007-03-13T00:17:00.000-07:00

Published: November 6, 2002
Source: Taiwan News

The National Health Research Institute (NHRI) on Tuesday confirmed research results that reveal the effect of cryptomonadales in lowering blood sugar and blood fat in diabetes patients.

The NHRI reported that after continuously taking doses of cryptomonadales for 30 days, 90 percent of research patients showed a 25 percent decline in blood fat, and the blood sugar levels of diabetes sufferers improved to within healthy limits.

NHRI research team director Su Yi-ren stated that cryptomonadales are a species of green algae, which, after long-established evidence of their ability to reduce blood fat and blood sugar, have now been proven to have those benefits.

The Department of Health, however, has not yet officially recognized green algae as a health food.

According to International Chlorella Co., cryptomonadales are a unicellular plant containing chlorophyll, vitamins and high levels of protein. When applied in medication, cryptomonadales have been used to cure or alleviate many kinds of chronic diseases, including cancer, anemia, lupus, sterility and so on. In order to gain scientific proof, International Chlorella Co. contracted National Cheng Kung University Hospital to conduct several experiments and to provide pilot research on human subjects.

Chien Chih-sian, deputy director of biotechnology and medical research for the NHRI, said that five years ago more than ten patients suffering from heart disease and diabetes were found to have seen an improvement in their health after taking green-algae products. Further research found that the curative effects were due to cryptomonadales.

Through clinical observation, it has been discovered that diabetes is strongly linked to high blood fat diseases, and current medication has serious side effects. It is reported that if the activating factor can be refined in cryptomonadales, it could be used to benefit diabetes patients.

During the tests, 30 test patients took 30 cryptomonadales doses each day for one month. Positive effects were noticeable after two weeks, the NHRI said, adding that after one month, 90 percent of the subjects had reduced blood fat levels by 25 percent.

The Bureau of Health Promotion under the Department of Health stated that an estimated 360,000 people in Taiwan suffer from diabetes without knowing it. People with diabetes are 17 times more likely to suffer retina deterioration. Therefore, the bureau urged people over 40 to be tested to find out if they have diabetes in order to reduce their chances of blindness.

Huang Kao-bin, a consultant for the Center for Disease Control, discovered that diabetes patients infected with dengue fever have a higher death rate. Huang indicated that diabetes will cause pathological changes to blood vessels, and dengue hemorrhage fever can cause bleeding and thromboplastin malfunctions, both affecting blood vessels. The reason diabetes patients have a higher susceptibility to these diseases' symptoms is still unknown.

According to the NHRI, diabetes is the fifth most common cause of death in Taiwan, with around 10,000 people dying of diabetes last year. Statistics from the Business Communications Co. show that the global market for diabetes medication exceeds US$11.7 billion.

At present, treatment for diabetes largely consists of medication and diet control, in combination with exercise. Diet control is considered the most important of these measures.

The NHRI and International Chlorella Co. will conduct a three-year research project to make use of scintillation proximity assay to sift cryptomonadales components and look for the activating factor to enhance body insulin reception, increase insulin activation and reduce blood fat.

Technorati Tag: Biotechnology pharmaceutical Diabetes Diabetic Malaysia food supplement Health & wellness

Susu Tepung GT&F boleh menurunkan gula darah

2006-12-28T15:53:00.000-08:00

Dua ujian klinikal "Double blind" telah dilakukan di Taiwan dan terbukti bahawa "Susu tepung GT&F" boleh menurunkan tahap gula darah bagi pesakit kencing manis tanpa memberi sebarang kesan sampingan.

Ujian "Double blind" di Hospital Tzu Chi,Taiwan

Beberapa tahun kebelakang ini, pakar-pakar perubatan di Taiwan telah menemui revolusi terunggul untuk merawat dan mengawal kencing manis.

Pencapaian ini dilihat berdasarkan tahap gula darah di kalangan pesakit kencing manis telah berkurangan dan terkawal selepas diberikan " Susu Tepung GT&F".

Keputusan ini dicapai melalui ujian "double blind" .

Ujian ini diketuai oleh Dr Kuo Shi-Wen.Ujian klinikal dijalankan di Hospital Besar Buddhist Xindian Tzu Chi Taipei, Taiwan.Penulis (Penterjemah Nota:Penulis adalah wartawan di Sin Chew Daily di Malaysia) telah pergi ke Hospital Tzu Chi Taipei dan menemubual secara ekslusif bersama dengan Dr Kuo Shi-Wen, Director, Bahagian Metabolisme dan Endocrinologi di
Buddhist Xindian Tzu Chi General Hospital, Taiwan.

Beliau berkata: " Kami telah melakukan persampelan dan eksperimen "double blind" di Hospital Tzu Chi, Taiwan. Tujuan eksperimen ini diadakan adalah untuk menilai reaksi dan keselamatan pesakit diabetis jenis 2 selepas diberi minum "Susu Tepung GT&F"

Sebab-sebab utama lain projek ini dilakukan adalah: Insulin yang dirembeskan oleh pankreas bagi pesakit Diabetis Jenis 2 biasanya berkuality rendah dan kurang sensitif. Bagi membuka sel reseptor agar gula darah dapat masuk ke dalam sel, insulin memerlukan bantuan Faktor Toleransi Glukosa ( GTF ) terutamanya Trivalen kromium, elemen dalam Faktor Toleransi Glukosa (GTF).

"Trivalen kromium" kebiasaannya kurang dalam darah pesakit diabetis jenis 2. Ini merupakan sebab pesakit diabetis menjadi semakin teruk.
Pakar-pakar perubatan Taiwan telah berjaya mengekstrak "trivalen kromium", ditambah ke dalam susu tepung dan dihasilkan sebagai "Susu Tepung GT&F".

Sasaran eksperimen ini adalah "Susu Tepung GT&F". Adakah susu tepung ini benar-benar dapat menurunkan dan mengawal gula darah pesakit diabetis? Jika ya, berapakah paras gula darah yang menunjukkan susu tepung tersebut mampu mengawal gula darah?

Keupayaan mengawal tahap gula darah pada haiwan

Eksperimen haiwan seperti eksperimen ke atas tikus, menunjukkan metabolisme gula darah dan lipid telah dipertingkatkan selepas tikus-tikus tersebut diberikan susu tepung yang mengandungi "trivalen kromium"

Trivalen Kromium berkurangan apabila usia meningkat

Eksperimen lain menunjukkan bahawa apabila umur pesakit diabetis meningkat, tahap trivalen kromium darah berkurangan.

Trivalen kromium berupaya mengawal peningkatan tahap gula darah

Pada 1997, Dr Anderson telah menjalankan satu kajian dan mendapati bahawa selepas diberikan susu tepung yang kaya dengan trivalen kromium (500-1000mcg). peningkatan tahap gula darah bagi pesakit diabetik jenis 2 berjaya dikawal.
Dos piawai Amerika : pengambilan 200mcg trivalen kromium di susu tepung sehari adalah mencukupi dan selamat.

Susu Tepung Faktor Toleransi Glukosa ( Susu Tepung GT&F ) tidak memberi sebarang kesan sampingan dan tidak mengandungi racun.
Sejak kejayaan eksperimen haiwan yang terbukti bahawa susu tepung ini benar-benar dapat menurunkan tahap gula darah pada haiwan, ujian ke atas pesakit diabetis jenis 2 pula dilakukan.

156 orang pesakit diabetik

Laporan terperinci ujian klinikal adalah seperti ditunjukkan di bawah:

Kami mengambil persakit diabetis jenis 2: lelaki dan perempuan, dengan umur antara 30 to 75 tahun.Ketika itu, mereka diberikan ubat menurunkan gula darah untuk 2 bulan yang lalu dan keadaan mereka stabil.

Kami dapat mengambil 156 orang pesakit untuk menyertai kajian ini.

Tahap FPG dalam tubuh pesakit adalah 140-250mg/d1 manakala tahap HbA1c adalah anatara 7.5%-12%.

Tahap trigliserida (asid lemak) ketika berpuasa bagi pesakit tersebut adalh kurang daripada 400mg/d1. Manakala Indeks Jisim Tubuh (BMI) adalah antara 20-35kg/m2.

Hanya pesakit yang menandatangani borang penyertaan akan disertakan.

Tempoh rawatan: 16 minggu ( 4 bulan ) . Ujian double blind : Kumpulan A dan Kumpulan B.

Penilaian terhadap kesan terapeutik: Pada minggu ke 16, terdapat perubahan tahap HbA1c level ;FPG; penolakan insulin(HOMA);tindak balas Sel B ( iaitu perembesan insulin); jumlah kolesterol, kolesterol baik (HDL-C), kolesterol tidak baik (LDL-C) dan tahap trigliserida pada pesakit kumpulan A.

Susu Tepung GT&F merupakan salah satu elemen nutrien untuk pesakit diabetik. Ia terbukti selamat dan terdapt kesan terapeutik.

Eksperimen diikhtiraf oleh jurnal antarabangsa

Berdasarkan pesakit perempuan daripada kumpulan A dan kumpulan B, kami mendapati pesakit yang telah diberikan susu tepung tersebut selama 16 minggu, tahap HOMA dalam badan menurun dengan mendadak. Walaubagaimanapun, kajian yang lebih mendalam perlu dilakukan untuk mengetahuio penyebab keputusan ini.

Kami telah mengeluarkan laporan eksperimen dan teleh dikemukakan dalam mesyuarat The Endocrinology Society and The Diabetes Association(EASD) pada tahun 2004. Sebagai tambahan, kami berbangga kerana laporan tersebut telah diterima dan diterbitkan dalam jurnal klinikal perubatan antarabangsa.

Eksperimen kedua

Di samping itu, kami juga telah menjalankan ujian klinikal yang lain. Beberapa perbezaan ciri-ciri eksperimen berbanding eksperimen pertama ditunjukkan dibawah:

Bilangan pesakit diambil : 40 orang pesakit; nisbah lelaki dan perempuan ialah 20:20. Semua adalah pesakit diabetis jenis 2.

Pesakit dibahagikan kepada dua kumpulan iaitu kumpulan A dan B. Pesakit kumpulan A diberikan susu tepung GT&F sementara pesakit kumpulan B diberikan susu tepung placebo (biasa)

Tempoh eksperimen: 16 minggu

Tempat Eksperimen: Hospital Tri-Service

Ini merupakan eksperimen kedua:

Latar Belakang Subjek Kajian	Susu Tepung GT&F (20 orang)	Placebo ( 20 orang )
Umur	54.2+-7.1	55.6+-8.2
Jatina (lelaki/perempuan)	10/10	10/10
BMI (Kg/Mz) Indeks Jisim Tubuh	25.2+-4.1	26.2+-3.2
Tempoh diabetik (Bulan)	58.1+-16.1	60.1+-15.2
Plasma gula darah ketika berpuasa (mmol/L)	9.72+-2.3	9.53+-3.1
Plasma insulin ketika berpuasa (pmol/L)	62.5+-31.2	56.7+-28.5
HbA1c (%)	9.3+-0.9	9.1+-1.1
Penolakan insulin ( HOMA-IR )	4.42+-1.82	4.17+-2.01
Sensitiviti insulin (SI,10-5min-1/pm )	0.21+-0.67	0.25+-0.52
Keefektiran glukosa(EG, MIN-1)	0.138+-0.49	0.126+-0.32
Reaksi insulin akut (AIR, PM)	222+-146.2	246+-126.8

Kesimpulan

Susu Tepung dengan Trivalen Kromium mempunyai kesan terapeutik, adalah selamat dan tiada kesan sampingan pada pesakit diabetis jenis 2.

Susu tepung ini boleh menurunkan tahap FPG, FPI dan HOMA pada pesakit lelaki. Kesimpulan ini dibuat berdasarkan perbandingan pesakit diabetis yang mengambil susu tepung placebo (biasa)

Eksperimen ini ditulis dalam bentuk laporan dan telah dipersembahkan pada mesyuarat The Endocrinology Society and The Diabetes Association (EASD ) 2005. Ia juga diterima dan diterbitkan dalam "Jurnal Metabolisme."

Bahagian 3: Makanan tidak sihat mudah menyebabkan penjakit jantung

Side Bar: Penerangan Terbaru Mengenai Kencing Manis
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Terjemah dari Sin Chew Jit Poh bertarikh 23hb Mar 2006
Technorati Tag: diabetis diabetik Diabetes Kencing Manis Malaysia

GT&F Milk Powder able to lower diabetics' blood glucose level

2006-12-18T19:40:00.000-08:00

Two "Double blind" clinical test were conducted in Taiwan and proved that " GT&F milk powder " able to lower diabetics' blood glucose level without any side effect.

Double blind test in Tzu Chi General Hospital,Taiwan

There is a revolutionary breakthrough on diabetes healing and control by Taiwan medical specialist recently.

The achievement is some diabetes patient able to lower and control their blood glucose level effectively by taking " GT&F Milk Powder ".

This accomplishment is acheived through a "double blind" test. The head of the team that conducted the experiment is Dr. Kuo Shi-Wen.

The venue of the clinical trial is at Buddhist Xindian Tzu Chi General Hospital, Taiwan.

The author of this article (Translator Note: The author of this article is a journalist with Sin Chew Daily in Malaysia) went to Tzu Chi General Hospital under a special arrangement to conduct an exclusive interview with Dr Kuo Shi-Wen. Who is Director of Division of Metabolism and Endocrinology with Buddhist Xindian Tzu Chi General Hospital, Taiwan.

He reveal that : We have done a randomized and double blind test in Tzu Chi General Hospital, Taiwan. The objective of the trial is to review the reaction and safety of diabetes patients after taking " GT&F Milk Powder ".

Another important reason for this project is: Insulin produced by pancreas of type 2 diabetes patients usually low quality and insensitive. In order to open the receptors of cells for the blood sugar to enter into the cells, this insulinhas to depend on the help from Glucose tolerance Factor ( GTF ) especially the Trivalent Chromium, an element in Glucose tolerance Factor (GTF) .

There is usually a "trivalent chromium" deficiency in the blood of type 2 diabetic patients. This is the reason the conditions of diabetics deteriorate.
Taiwan's medical specialist has successfully extract trivalent chromium and add it to milk powder to become " GT&F Milk Powder "

The target of our experiment is this GT&F MilkPowder. Can the milkpowder really reduce and control the blood sugar levels in diabetic patients after consumption? If yes, at what level is the milk powder able to control the blood sugar?

Ability control blood glucose level in animal

Animal test, e.g. : rat indicated that its has improved its glucose and lipid metabolism after taking milk powder with trivalent chromium.

Elderly have less Trivalent Chromium

Other research show that when a type 2 patient aged, and become elderly, trivalent chromium within their body would reduced with age.

Trivalent Chromium able to control increase in blood glucose levels

In 1997, a research conducted by Dr Anderson indicated that after a type 2 diabetes patient taking milk powder with rich trivalent chromium (500-1000mcg). The patient successfully control their blood glucose level and prohibit their blood glucose level to increase.
According to US standard : 200mcg of trivalent chromium in milk powder daily is sufficient and safe.
Glucose tolerance Factor Milk Powder ( GT&F Milk Powder ) have no side effects and is non-toxic.
As it has been proven that such milk powder able to lower animal glucose level. Thus, we now conducted a clinical test on type 2 diabetes patients.

156 Diabetes Patients

The detail of the clinical trial are as follow:

We have recruited participant from type two diabetes patients: Male or female, age between 30 to 75.

Currently, they are consuming oral medicine for diabetes for the pass 2 months and their blood glucose level has been stablelise.

We have successfully recruited 156 patients to participate in this trial.

Patients' FPG between 140-250mg/d1 and HbA1c level between 7.5-12%.

Patients' empty-stomach triglyceride level were less than 400mg/d1. Body Mass Indexes (BMI) were between 20-35kg/m2.

Only patients who gave informed consent were recruit as study participant.

Duration of treatment: 16 weeks ( 4 months ) . Double blind test : Group A and Group B.

Evalution of therapeutic effects : On the 16th weeks, group A patients' HbA1c level has changed. On the 16th weeks, all group A's patients' FPG;insulin rejection(HOMA); Cell B; Total Cholesterol, HDL-Cholesterol, LDL-Cholesterol and triglyceride level has changed.

GT&F Milk powder is one of the nutrition supplement for diabetic patients. It has proven to be save and have therapeutic effects.

Recognition from international journal

HOMA levels from Group A and Group B female patient has substantially reduced after 16 weeks of taking the milk powder, further research required to be done to find out the reason of such improvement.

We have produced a report on such clinical trial and pusemted it on Annual Meeting of The Endocrinology Society and The Diabetes Association of The R.O.C. in 2004(EASD), and has been accepted and published by an international clinical trial journal. We feel honor on this.

Second Trial

Other than the above, we have conducted another double blind test. Some of the distinguished features of the experiment are shown as follow:

Number of paticipants : 40. Ratio between male and female is 20:20. All are type 2 diabetes patients.

Patients were divided into Group A and Group B: Group A patients consumed GT&F Milk Powder whereas Group B patients consumed Placebo milk powder.

Duration: 16 Weeks

Venue : Tri-Service General Hospital

Below are our second trial:

Participants'Details	GT&F Milk Powder (20 persons)	Placebo ( 20 persons )
Age	54.2+-7.1	55.6+-8.2
Sex (Male/Female)	10/10	10/10
BMI (Kg/Mz)	25.2+-4.1	26.2+-3.2
Diabetes aged (Months)	58.1+-16.1	60.1+-15.2
Empty-stomach blood glucose level (mmol/L)	9.72+-2.3	9.53+-3.1
Empty-stomach blood insulin (pmol/L)	62.5+-31.2	56.7+-28.5
HbA1c	9.3+-0.9	9.1+-1.1
Insulin Resistance ( HOMA-IR )	4.42+-1.82	4.17+-2.01
Insulin Sensitivity (SI,10-5min-1/pm )	0.21+-0.67	0.25+-0.52
(EG, MIN-1)	0.138+-0.49	0.126+-0.32
(AIR, PM)	222+-146.2	246+-126.8

Conclusion:

Milk Powder with Trivalent Chromium has therapeutic effects, safe and without side effect on type 2 diabetic patients.
For male patients: Such Milk Powder able to lower FPG, FPI and HOMA levels. This is a conclusion after a comparison with diabetic patients consuming placebo milk powder.
Such trial has been compile in report and presented at the Annual Meeting of The Endocrinology Society and The Diabetes Association of The R.O.C. 2005(EASD meeting), and has been accepted and published by Metabolism Journal.

Published by Sin Chew Daily dated 23 March 2006 (Part 4) under the courtesy of GTF Worldwide Sdn Bhd
Excerpt and translated by DiabetesMilkPowder.com

Part 3 :Unhealthy Food Cause Heart Diseases Easily

Side Bar: A New Explanation For Diabetes

Technorati Tag: Biotechnology pharmaceutical Diabetes Diabetic Malaysia food supplement Health & wellness GT&F Milk Powder Chromferrin

Makanan tidak sihat mudah menyebabkan penjakit jantung

2006-11-23T20:40:00.000-08:00

Konsultan Pulmonari dan Penjagaan Kritikal Hospital Besar Kuala Lumpur Dato Dr Jeyaindran Sinnadurai menyatakan bahawa gaya hidup masyarakat pada hari ini telah banyak berubah. Gaya hidup dan makanan yang tidak sihat membawa kepada atherosclerosis iaitu pembunuh pertama. Amalan gaya hidup moden seperti diet yang tidak sihat, penambahan berat badan dan kurang bersenam merupakan faktor utama menyebabkan sindrom metabolik dan embolisme arteri jantung.

INFLAMASI ARTERI JANTUNG

Ketika ditemubual, Dato Dr Jeyaindran Sinnadurai, Pakar Kardiologi dari Hospital Besar Kuala Lumpur membincangkan tentang "Diet dan Inflamasi: Hubung kait dengan penyakit metabolik dan kardiovaskular". 20 tahun yang lalu, para saintis telah mengkaji mekanisme pembentukan atherosclerosis dan kesan pemakanan keatas mekanisme metabolisme. Berdasarkan kajian tersebut, saintis boleh mengenalpasti jenis makanan yang dimakan oleh itu, nutrien yang diperlukan dapat diserap dalam badan untuk meningkatkan kesihatan jantung.

Makanan yang terbaik untuk melindungi jantung adalah terdiri daripada lima jenis bijirin, sayur-sayuran dan buah-buahan. Pengambilan daging merah, produk susu penuh krim dan makanan yang manis patut dielakkan.

Eksperimen saintifik membuktikan bahawa diet yang sihat disamping gaya hidup yang sihat boleh mengurangkan risiko embolisme arteri jantung sebanyak 83%. Risiko seseorang wanita menghidap diabetis juga dapat dikurangkan sebanyak 91% manakala risiko kanser kolon pada lelaki juga dapat dikurangkan sebanyak 71%. akan tetapi, kehadiran makanan barat dalam pasaran, telah menyebabkan pengambilan sayur-sayuran dan buah-buahan pada masa ini tidak mencapai keperluan badan.

Terdapat saintis yang mengatakan bahawa pengambilan terlalu banyak makanan yang tidak sihat merupakan salah satu penyebab utama inflamasi arteri jantung. Apabila arteri mengalami inflamasi, embolisme arteri jantung akan terbentuk.

PELBAGAI KEADAAN POST PRANDIAL

Post-prandial merupakan satu keadaan dimana seseorang itu kekal dalam keadaan tertentu dalam tempoh masa yang lama dan seterusnya ia akan membawa masalah atherosclerosis.

Perbezaan keadaan post-prandial ditunjukkan seperti di bawah:

*Hypertriglyceridaemia dalam darah
*Penularan Carotid Intima Media pada pesakit diabetik
*atau hyperglycaemia
*atau hyperlipidaemia
*Sejenis enzim yang dikenal sebagai dimethylarginine akan muncul dalam plasma darah. Enzim ini berupaya merosakkan lapisan internal arteri jantung. apabila lapisan internal cedera, arteri tersebut akan mudah terhalang.

Walaupun bergitu, pengambilan makanan dan minuman secara berlebihan tetapi pada masa yang sama mengambil banyak sayur-sayuran akan dapat juga melindungi lapisan arteri jantung daripada tercedera.

Mengapa pengambilan daging secara berlebihan akan merosakkan lapisan internal arteri? Keadaan ini disebabkan oleh pengumbulan lemak dan kolesterol pada lapisan internal boleh mengakibatkan inflamasi/ keradangan pada lapisan tersebut. Kesannya, lapisan internal akan menjadi tidak kuat dan lemak mudah berkumpul pada lapisan tersebut. Pengumpulan lemak pada lapisan tersebut merupakan faktor utama berlakunya embolisme arteri jantung.

Manusia pada hari ini makan beberapa hidangan sehari, dan ini bermaksud badan mengalami keadaan post-prandial sebanyak beberapa kali sehari. Apabila masa berlalu, lapisan internal arteri jantung akan menyebabkan kecederaan dan akhirnya membawa kepada masalah embolisme pada arteri.

PENYEBAB INFLAMASI/KERADANGAN PADA ARTERI JANTUNG

Pengambilan daging dan gula yang tinggi akan mendorong kepada masalah inflamasi arteri jantung kerana:

*Lemak dan gula darah akan menyebabkan lapisan internal arteri jantung berkeadaan oksidan. Ini akan merangsang sekurang-kurangnya 125 gen di mana gen tersebut akan menggalakkan lagi inflamasi berlaku.

*Gula darah juga berupaya merangsang sel inflamatori dalam badan. Jadi, ia akan menyebabkan inflamasi lapisan internal arteri jantung. Dengan kata lain, cytokine inflamatori akan dirangsang oleh gula darah dan menyebabkan inflamasi.

*Sel terlalu aktif

Selepas mengambil terlalu banyak makanan dan minuman, sel pada lapisan internal arteri jantung akan menjadi aktif. Di samping itu, molekul pada plasma akan menjadi lebih pekat. Kemudian, sel inflamasi akan bertindak agresif. Ini menebabkan inflamasi pada lapisan internal arteri jantung.

*Keadaan oksidan pada arteri jantung

Selepas mengambil makanan tinggi lemak dan gula, arteri jantung akan mengalami keadaan oksidan. Justeru, sensitiviti insulin akan menjadi kurang. Dalam erti kata yang lain, insulin tidak mampu memasuki sel dengan mudah. Selepas beberapa tahun, hyperglycaemia akan terbentuk. akhirnya, ia akan membawa kepada sindrom metabolik dan pembentukan diabetis.

MAKANAN ANTI-OKSIDAN PATUT DIAMBIL SELEPAS MAKAN

Selepas makan, nutrien yang tercerna akan diedarkan ke salur darah. Selepas itu, amaun sel inflamatori, sel neutrophilik dan bahan oksidan akan meningkat secara signifikan dalam darah pada waktu itu.

Para saintis juga mendapati dengan mengambil sayur-sayuran, buah-buahan dan fiber dalam kuantiti yang banyak akan berupaya menentang " gelombang oksidan" dalam badan kerana ia mengandungi bahan anti-oksidan.

Jika asid lemak omega-3 diambil, risiko menghidap penyakit kardiovaskular akan berkurangan sebagaimana asid lemak omega-3 boleh menghalang inflamasi pada lapisan internal arteri jantung.

Keadaan oksidan memainkan peranan penting dalam pembentukan atherososclerosis. Oleh yang demikean, terdapat pelbagai produk penjagaan kesihatan anti-oksidan dalam pasaran. Pihak produk tersebut mendakwa ianya mampu mengelakkan penyakit kronik termasuklah gangguan arteri jantung.

Akan tetapi, adakah ini benar?

Produk penjagaan kesihatan anti-oksidan

Tidak lama dahulu, satu eksperimen menentukan bahawa pengambilan produk penjagaan kesihatan vitamin E boleh meningkatkan risiko kematian.

Ini merupakan eksperimen terbesar yang melibatkan 12,504 orng mati akibat pengambilan produk penjagaan kesihatan vitamin E secara berlebihan. Liputan lain pula menunjukkan terdapat ramai orang yang mengambil produk vitamin E tetapi tiada kesan terapeutik diperhatikan. akan tetapi, pengambilan produk penjagaan kesihatan vitamin E yang kurang daripada 400iu dapat mengurangkan risiko kematian secara signifikan.

Oleh itu, produk penjagaan kesihatan yang asli dapat bertindak secara efektif tetapi hanya boleh diamabil dengan pengesahan daripada Kementerian Kesihatan atau pakar perubatan. Ini bermaksud kita perlulah mengambil berat terhadap dos pengambilan sesuatu produk.

Penyakit mudah dihidapi oleh orang yang obes

Makanan yang mengandungi tinggi lemak dan daging akan menyebabkan obesiti di mana lemak akan berkumpul di sekitar organ internal terutamanya abdomen menyebabkan buncit.
Mereka yang obes terdedah kepada penyakit berikut:

*Apabila lemak yang banyak berkumpul di bahagian organ dan abdomen, inflamasi yang tidak menunjukkan simptom akan terbentuk dengan mudah di seluruh badan.
*Mereka juga terdedah kepada gangguan metabolik yang serius.
*Mereka yang mempunyai adipositi abdominal akan mudah terjejas disebabkan oleh inflamasi lapisan internal arteri.

Para saintis Kanada telah menjalankan eksperimen dimana perserta yang kesemuanya terdiri daripada lelaki dan perempuan yang obes mengurangkan pengambilan makanan berlemak tetapi mengambil banyak sayur-sayuran dan buah-buahan. Selepas 6 tahun, berat badandan saiz pinggang mereka berkurangan.

Walau bagaimanapun, kedua-dua pakar perubatan dan pakar pemakanan berpendapat bahawa ini merupakan berita baik jika pesakit diabetik mengambil elemen nutrien yang dapat membantu menurunkan tahap gula dan mengelakkan diabetis.

Beberapa tahun kebelakang ini, banyak syarikat gergasi farmaseutikal menemui dan menghasilkan pelbagai jenis ubat yang membantu menurunkan tahap gula darah. Ia dikenali sebagai rawatan baris pertama.

Rawatan baris kedua pula adalah pengambilan elemen nutrien seperti Susu Tepung GT&F yang mana boleh didapati dalam pasaran. Produk ini boleh mengurangkan tahap gula darah dan mengelakkan pembentukan diabetis kerana ianya dapat meningkatkan sistem keimunan badan manusia.

Terjemah dari Sin Chew Jit Poh bertarikh 22hb Mar 2006 (Bahagian 3)

Bahgian 2: Ubat kencing Manis dan kesan sampingannya

Bahagian 4: Susu Tepung GT&F boleh menurunkan gula darah

Technorati Tag: diabetis diabetik Diabetes Kencing Manis Malaysia Penakit Jantung Sakit Jantung

Unhealthy Food Cause Heart Diseases Easily

2006-11-23T20:34:00.000-08:00

Consultant Pulmonary and Critical Care Physician of Kuala Lumpur General Hospital, Dato Dr Jeyaindran Sinnadurai pointed out that the lifestyle of people has changed a lot. Unhealthy lifestyles and food have made atherosclerosis our number one killer. Unhealthy diet, weight gained and lack of exercise of the modern lifestyle are the main factors causing metabolic syndromes and embolism of the heart arteries.

INFLAMMATION OF THE HEART ARTERIES

During an exclusive interview with Sin Chew Daily, Dato Dr Jeyaindran Sinnadurai spoke about "Diet and inflammation : A Link To Metabolic And Cardiovascular Disease."

In the past 20 years, scientists have been researching the mechanism of the development of atherosclerosis and the effects of food nutrition on the mechanism of the metabolism. From these researches, scientists are able to find out the type of food to eat so that essential nutrients can be absorbed to strengthen the health of the heart.

The best food for cardiovascular protection is the five cereals, vegetables and fruits. High intake of read meat, full cream milk products and sweet food should be avoided.

Scientific research proved that healthy diet plus healthy lifestyle can reduce the risk of heart arteries embolism for as high as 83%. The risk of diabetes in women can be reduced by 91% while risk of colon cancer in men can be as high as 71%. Nevetheless, due to the invasion of western food into our market, the vegetables and fruits intake by people today do not meet their body requirement.

Some scientist also said that too much unhealthy food is one of the main causes for inflammation of the heart arteries. Once the arteries inflamed, embolism of heart arteries develop.

VARIOUS POST-PRANDIAL STATE

Post-prandial state means that if a person maintains in such a state for a long period of time, it will results in atherosclerosis. Post-prandial states have diferent type as follow:

Hypertriglyceridaemia in the blood.
Expansion of the Carotid Intima Media in diabetic patients
or hyperglycaemia
or hyperlipidaemia
An enzyme is able to damage the internal layer of the heart arteries. When the internal layer is injured, the respective arteries will be blocked easily.

Nevertheless, eating and drinking excessively, but at the same time eating a lot of vegetables, will also protect the internal layer of the heart from injuries.

Why high intake of meat will damage the internal layer of the heart arteries? This is because the accumulation of fats and cholesterol in the internal layer will result in the inflammation of internal layer. Once inflammation developed, the internal layer become uneven and fats accumulate on the layer easily. The accumulation of fats in the internal layer is the main factor of the embolism of the heart arteries.

People today eat several meals a day, which means that the body is at the post-prandial state several times a day. As time passes, the internal layer of the heart arterioes will be injured ands finally leads to embolism of the arteries.

THE CAUSE OF THE INFLAMMATION OF THE HEART ARTERIES

High intake of meat and sugar will lead to the inflammation of the heart arteries because:

Fats and blood sugar will cause the internal layer of the heart arteries to be in oxidative state. This will stimulate at least 125 genes which are able to induce inflamation.
Blood sugar is also able to stimulate the inflammatory cells in the body.

So, this will stimulate the inflammation of the internal layer of the heart arteries. In other words inflamatory cytokines will be stimulated by blood sugar and cause inflammation.

The cells are very active

After excessive eating and drinking, the cells in the internal layer of the heart arteries are very active. Besides that, molecules in the plasma will be highly concentrated. Next, inflammatory cells will act on a large scale. This will induce the inflammation of the internal layer of the heart arteries.

Oxidant state of the heart arteries

After taking food high in fat and sugar, heart arteries will be in an oxidant state and inflammatory state. Thus, the sensitivity of insulin is reduced. In other words, the insulin is not able to enter the cells easily. Over the years, hyperglycaemia develop. In the end, this leads to metabolic syndromes and development of diabetes.

ANTIOXIDANT FOOD SHOULD BE CONSUMED AFTER MEAL

After a meal, digested nutrients circulate in the blood stream. Then, the amount of inflammatory cells, neutrophilic cells and oxidative substanceas will increase significantly in the blood during this time.

Scientists also discovered that consuming a large quantity of vegetables, fruits and fibers is able to resist the "oxidant wave" in the body because they contain antioxidant substances.

If omega-3 fatty acid (fish oil) is also consumed, the risk of cardiovascular diseases can also be reduced, as omega-3 fatty acid can ease the inflammation of the internal layer of the heart arteries.

Oxidant state plays an important role in the development of artherososclerosis. Therefore, a variety of antioxidant health care products are available in the market. They are claimed to be able to prevent chronic disease, including heart arteries disorder.

Nevertheless, is this the truth?

Antioxidant health care product

Not long ago, an experiment indicated that high intake if vitamin E health care products might increase the risk of death.

This is a large scale experiment which revealed that 12,504 people died of high intake of vitamin E health care products. Another discovery showed that many people consumed vitamin E products but no therapeutic effects were observed. Nevertheless, for low intake of vitamin E health care products, such as less than 400iu, the risk of death is significantly reduced.

Therefore, health care products of genuine quality are effective but they can only be consumed after their effectiveness is proved by the Ministry of health or medical specialists. In the meantime, we should be cautious about dosage of consumption of the products.

Obese individual get diseases more easily

Food high in fats and meat will result in obesity where the fats accumulate around the internal organs, especially the abdomen, leading to pot-belly.

Those suffer from obesity are prone to the following diseases:

When a large amount of fats is accumulated in the organs and abdomen, inflammation on the whole body that do not show any symptoms initially will develop easily.
They are also prone to the most serious metabolic disorders.
Those with abdominal adiposity are afected by unhealthy food more easily, leading to inflammation of the internal layer of arteries.

Canadian scientists have carried out an experiment where the participants who are all obese man and women, reduced their intake of fatty food but ate a lot of vegetables and fruits. After 6 years, their weights and waist sizes were reduced.

However, both medical specialists and nutritionists think that it would be good news if diabetetic patient is able to take reliable nutrition supplements that help to reduce blood sugar levels and prevent diabetes.

In recent years, many large pharmaceutical companies discover and produce a variety of drugs which help to reduce blood sugar levels. This is called first line treatment.

Second line treatment is the consumption of nutrition supplements, such as GT&F Milk powder which is available in the market. This product can reduce blood glucose levels and prevent the deterioration of diabetes because it can strenthen the immune system of the human body.

Published by Sin Chew Daily dated 22 March 2006 (Part 3) under the courtesy of GTF Worldwide Sdn Bhd
Excerpt and translated by DiabetesMilkPowder.com

Part 2 :Drugs for diabetes and it side effects

Part 4 : GT&F Milk Powder able to lower diabetics' blood glucose level

Technorati Tag: Biotechnology pharmaceutical Diabetes Diabetic Malaysia food supplement Health & wellness GT&F Milk Powder Heart Cardiovascular Chronic Chromferrin

Ubat kencing Manis dan kesan sampingannya

2006-11-22T00:10:00.000-08:00

Diabetis tidak boleh diubati secara kekel. Rawatan yang paling ideal adalah melalui pengawalan keterukan penyakit dan menurunkan tahap gula darah. Walau bagaimanapun, ianya bukan mudah dilakukan. Keadaan tersebut adalah (1) pesakit mesti memahami sepenuhnya kepentingan "menurunkan gula darah" (2) pesakit mesti mempunyai keinginan yang kuat untuk mengawal selera makan dan mengelakkan diri daripada makan dan minum secara belebihan (3) pesakit mesti memdapatkan nasihat pakar diabetik, pakar mata, pakar terpi diet, pakar terapi kaki dengan lebih kerap agar pesakit dapat memahami keadaan kesihatan mereka dengan jelas.

MENURUN GULA DARAH TUGASAN PENTING

Ketika ditemubual, Pengarah Perkhidmatan Kesihatan Kementerian Pertahanan Maj Jen Dato (Dr) Sulaiman Bin Abdulan telah mendapati bahawa Pusat penyelidikan dan Diabetis di United Kingdom telah menemui risiko "kompikasi kapilari" yang mampu dikurangkan jika pesakit diabetik mangawal tahap gula dengan ketat.

Kurangkan angiopathy major dan minor

Penemuan lain oleh pusat tersebut adalah dengan kawalan ketat terhadap paras tekanan darah (sasarkan kurang daripad 130/70 mmHg), risiko "komplikasi major dan minor kapilari" dapat dikurangkan.Pusat tersebut juga menekankan bahawa pesakit diabetik perlu diberikan perhatian lebih terhadap penglihatan dan perlu menjalani pemeriksaan sama ada mengalami retinopathy atau tidak.Maj Jen Dato (Dr) Sulainman Bin Abdullah juga memberitahu bahawa penyakit kaki pada pesakit diabetik adalah merupakan masalah yang serius. Mereka sepatutnya mendapatkan nasihat pakar dengan lebih kerap bagi memeriksa keadaan kaki mereka kerana mereka kerap mengalami:

*sakit kaki berdenyut

*Ulser atau otot mati

*Neuropathy pada kaki

Kawalan ketat pengambilan diet

Pengambilan makanan yang dikawal ketat adalah salah satu cara yang penting untuk mengawal diabetes daripada bertambah teruk dan dapat menurunkan tahap gula darah.

*Kurangkan pengambilan makan tinggi kalori dan kurangkan pengumpulan lemak pada tubuh dan kekalkan berat tubuh ideal.

*Kurangkan pengambilan makanan berlemak untuk melambatkan pembentukan atherosclerosis.

*Kurangkan mengambil makanan manis untuk mengelakkan peningkatan kuantiti gula darah.

*Meningkatkan pengambilan sayur-sayuran, terutamanya sayuran tinggi serat, untuk membantu menurunkan tahap gula darah. Selain itu, ia juga untuk membantu mengelakkan penurunan gula secara tiba-tiba kerana penurunan gula darah secara mendadak akan menyebabkan hipoglisemia.

UBAT MENURUNKAN GULA DARAH

Terdapat beberapa jenis ubat yang digunakan untuk menurunkan tahap gula darah dan ubat yang paling penting adalah ubat daripada kumpulan sulphonylureas dan kumpulan biguanides.

Sulphonylureas

Mekanisme ubat kelas ini adalah untuk menambahkan semula perembesan insulin. Dalam erti kata yang lain, alpha sel pada pankreas pesakit masih berupaya mengeluarkan sedikit insulin tetapi amaun tersebut tidak mencukupi. Oleh itu, kumpulan ubatan ini akan mengglakkan perembesan insulin daripada pankreas. Terdapat beberapa jenama dalam pasaran daripada kumpulan ini tetapi kesan therapeutikny tetap sama.

Kesan Sampingan
*Risiko tekanan darah rendah pada pesakit yang berumur yang mana mengambil ubat ini dalam satu tempoh yang agak lama. Oleh itu, ubat kelas ini mestilah dipreskripsikan oleh pakar perubatan terlebih dahulu.

*Ubat kelas ini mengallakkan penambahan berat badan. Keadaan ini semakin teruk pada pesakit yang obes yang mana kegemukan boleh menyebabkan peningkatan kerintangan insulin dalam badan. Ini disebabkan oleh sel diliputi oleh lapisan lemak. Oleh yang demikian, ia menyebabkan pankreas sukar untuk membuka "pintu" (reseptor) pada sel untuk membenarkan gula darah memasuki sel tersebut.

Biguanides

Ketika ini, terdapat satu sahaja jenama di pasaran untuk kumpulan ubat ini iaitu, Metformin. Tindak balas ubat ini adalah untuk mengurangkan sumber gula darah, yang mana ianya membantu insulin untuk membenarkan lebih banyak gula darah memasuki sel. Pada masa yang sama, ubat ini juga dapat menguatkan tisu dalam badan manusia oleh itu lebih banyak gula darah dapat digunakan. Ubat daripada kelas ini mempunyai beberapa kebaikan berikut:

*Sesuai untuk pesakit diabetik Jenis 2.

*Sesuai untuk pesakit diabetik yang obes. Ubat ini adalah ubat pertama yang menjadi pilihan pakar perubatan untuk diberikan kepada penyakit diabetik.Kesan sampingan ubat kelas ini adalah ketidakselesaan pada perut dan usus. Justeru, ubat ini perlu diambil selepas makan. Walau bagaimanapun, mereka yang mempunyai masalah buah pinggang tidak boleh mengambil ubagt ini.

Thiazolidinediones

Ubat kelas ini berupaya meningkatkan sensitiviti insulin. Dengan kata lain, ia membantu gula darah memasuki sel denganlebih mudah. Jika ubat sulphonylureas dan biguanides tersebut tidak dapat menurunkan gula darah dengan efektif, maka Thiazolidinediones digunakan.

Acarbose

Tahap gula darah sudah semestinya meningkat selepas pesakit mengambil makanan. Ubat kelas ini berupaya menurunkan tahap gula darah tinggi selepas makan.Kesan sampingannya adalah kembung perut.

Insulin

Hampir 25% pesakit diabetik memerlukan suntikan insulin. Insulin merupakan hormon polipeptida. apabila insulin bertemu dengan asid gastrik, ia menjadi tidak efektif. Oleh itu, pesakit perlu memasukan insulin ke dalam badan melalui suntikan.Selepas suntikan insulin, tahap gula darah pesakit akan dipantau. Tahap gula darah ketika kenyang adalah 4mmol/L hingga 9mmol/L. Kebanyankan pesakit sepatutnya menggunakan insulin pada kesan pertengahan dan melakukan suntikan insulin 2 kali sehari.Ubat-Ubat yang di senaraikan di atas adalah kaedah yang berlainan untuk mengurangkan tahap gula darah bagi pesakit diabetik. Walau pun terdapat kesan terapeutik yang tinggi, setiap jenis ubat mempunyai kesan sampingan.

Kamus kecil

Ujian Double-blind

Ujian Double-blind merupakan keadaan eksperimen yang istimewa di mana kedua-dua penyelidik (atau doktor) dan peserta (atau pesakit) tidak mengetahui prosedur eksperimen dan ubat yang diambil. Oleh itu mana-mana pesakit yang mendapat kesan placebo semasa eksperimen dapat dielakkan.

Perkaitan antara Faktor Toleransi Glukosa dan diabetis

Faktor Toleransi Glukosa (GTF) kebiasaanya hadir dalam pelbagai tisu dalam badan manusia. Fungsi utamanya adalah untuk mengekalkan metabolisme gula dalan badan. Dengan koordonasi insulin dan reseptor insulin, faktor toleransi glukosa akan mengangkut glukosa dari darah ke sel-sel dalam badan manusia. Faktor Toleransi Glukosa merupakan bahan semulajadi yang diperlukan oleh insulin untuk mengaktifkan reseptor insulin. Faktor Toleransi Glukosa mangandungi bahan seperti vitamin, mineral dan asid amino dengan trivelen kromium sebagai elemen pusat.Ketidakcukupan pengambilan trivalen kromium pada satu tempoh yang lama akan menyebabkan pengurangan Faktor Toleransi Glukosa yang dihasilkan secara semulajadi oleh badan. Oleh sebab itu, kerintangan insulin dan simptom klinikal diabetes terbentuk. Kehadiran gula yang berlebihan dalam urin akan memerlukan lebih banyak lagi Faktor Toleransi Glukosa. Ini membawa kepada kekurangan trivalen kromium yang serius dan akhirnya menyebabkan kehilangan fungsi buah pinggang. Ini juga merupakan penyebab utama pesakit kencing manis turut mengalami masalah buah pinggang.Kekurangan trivalen kromium akan membawa kepada kerintangan insulin yang memberi kesan kepada kenormalan metabolisme. selain daripada pembentukan diabetis, ia juga memberikan simptom klinikal seperti tahap gula darah yang abnormal dan penyakit kardiovascular.

Susu Tepung Faktor Toleransi Glukosa

Pada 15 Januari 2006, kumpulan pelawat Malaysia telah mengadakan lawatan ke Taiwan untuk mengetahui tentang pembangunan susu tepung yang dihasilkan khususnya untuk pesakit diabetik Susu Tepung GT&F yang mengandungi Faktor Toleransi Glukosa.

Dr. Kuo Shi-Wen, pakar dalam endokrinologi dan metabolisme di Hospital Taipei City Xindian Tzu Chi,sebagai ketua pasukan ujian double blind yang mengunnakan Susu Tepung Faktor Toleransi Glukosa telah dilakukan. Keputusan ujian sungguh menakjubkan. Seramai 156 pesakit diabetik jenis 2, lelaki dan perempuan telah melalui ujian ini. Hasil ujian mendapati tahap gula telah menurun secara signifikan selepas 4 bulan mengambil susu tepung ini. Pada waktu yang sama, keadaan kerintangan insulin kebanyakan pesakit telah menunjukan perubahan yang baik.

Keputusan eksperimen double blind telah mendapat pujian pada Konferens Diabetes Antarabangsa 2004 dan keputusan tersebut telah diterbitkan dalam "Jurnal Antarabangsa amalan Kinikal."

Eksperimen di Universiti Kebangsaan Chung Hsing

Prof Jei-Fu Shaw, presiden University Kebangasaan Chung Hsing, doktor falsafah dalam bidang biokimia dan ialah ahli fellow Persatuan Sains Lanjutan Amerika (AAAS).

Pihak university menjalankan kajian ke atas tikus dengan mengunakan Susu Tepung Faktor Toleransi Glukosa. Selepas 4 bulan, mereka juga mendapati Susu Tepung Faktor Toleransi Glukosa berupaya mengawal diabetis daripada melarat dan menurunkan tahap gula darah tanpa sebarang kesan sampingan.

Terjemah dari Sin Chew Jit Poh bertarikh 21hb Mar 2006 (Bahagian 2)

Bahagian 1: Diabetis dan komplikasi diabetik

Bahagian 3: Makanan tidak sihat mudah menyebabkan penjakit jantung

Technorati Tag: diabetis diabetik Diabetes Kencing Manis Malaysia

Diabetis dan komplikasi diabetik

2006-11-21T00:19:00.000-08:00

Kencing manis atau diabetis juga dikenali sebagai "Ibu Segala Penyakit". Menurut statistik WHO, dianggarkan terdapat 250 juta orang pesakit diabetik di seluruh dunia. Empat orang mati akibat diabetis atau komplikasi diabetik pada setiap minut. Di setiap negara, terdapat 6% hingga 15% populasi menderita diabetis dan situasi ini paling serius di Asia. Saban tahun di seluruh dunia, ratusan billion dolar US diperutukkan untuk perubatan penyakit kencing manis.

BILANGAN PESAKIT DIABETIK TERTINGGI DI ASIA

Pada abad ke-21, terutamanya pada tahun 2025, diabetis mellitus merupakan musuh utama kesihatan manusia yang sukar dihapuskan kerana diabetis adalah akar kepada semua penyakit dan musibah.

Menurut statistik Petubuhan Kesihatan Sedunia (WHO), pada tahun 2003, secara kasarnya terdapat 189 juta orang pesakit diabetik di seluruh dunia. Pada tahun 2025, bilangan pesakit kencing manis akan meningkat kepada 324 juta orang. Dengan perkataan lain, dalam tempoh 22 tahun yang akan datang, bilangan pesakit diabetik akan meningkat sebanyak 72%.

Di seluruh dunia, Asia mempunyai bilangan pesakit kencing manis tertinggi. Bilangan pesakit diabetik meningkat kepada 91%, iaitu daripada 81.8 juta orang pada 2003 kepada 156.1 juta orang pada tahun 2025.

Temubual terkini, Pengarah Perkhidmatan Kesihatan Kementerian Pertahanan Major Jeneral Dato (Dr) Sulaiman Bin Abdullah mengemukakan beberapa komplikasi diabetis:

Sakit jantung

Termasuk atherosclerosis dan myocardial infarction, risiko kematian adalah 2 hingga 4 kali lebih tinggi di kalangan pesakit kencing manis berbanding mereka yang tidak menghidapi diabetis.

Strok

Risiko strok adalah 2 hingga 4 kali lebih tinggi pada pesakit diabetik berbanding orang normal.

Tekanan darah tinggi

Dianggarkan sebanyak 60% hingga 65% pesakit kencing manis mederita tekanan darah tinggi.

Penyakit terminal buah pinggang

Dianggarkan sebanyak 20% hingga 40% pesakit diabetik menghidapi nephropathy. Diabetis juga merupakan peyebab utama penyakit terminal buah pinggang.

Kebutaan primer

Diabetis merupakan penyebab kebutaan primer yang dialami mereka yang berumur antara 20 dan 70 tahun manakala retinopathy merupakan penyebab utama kebutaan.

Penyakit sistem saraf

Dianggarkan 60% hingga 70% pesakit diabetik mederita pelbagai jenis penyakit yang berkaitan dengan sistem saraf.

APA ITU DIABETIS
=================

Pancreopathy

Kencing manis atau diabetis adalah penyakit kronik. Apabila pankreas badab tidak berupaya merembeskan insulin atau menggunakan insulin dengan efektif, ini menyebabkan tahap gula darah meningkat dan diabetis terbentuk. Hiperglisemia dan lain-lain perubahan pathologikal metabolisme akan merosakkan fungsi normal beberapa organ dalam badan, terutamanya sistem saraf dan sistem vaskular.

Pesakit diabetik Jenis 1

Terdapat dua jenis diabetis mellitus:

Diabetis Jenis 1 : Badan manusia tidak berupaya merembeskan insulin.

Sebab: Ini mungkin disebabkan sel manusia membunuh sesama sendiri dalam sistem keimunan badan. Sebanyak 10% pesakit diabetik menghadapi diabetis Jenis 1 dan kebanyakannya kanak-kanak.

Diabetis Jenis 2 : Apabila kualiti insulin yang dirembeskan oleh pankreas agak teruk, ia tidak berupaya membuka atau merangsang reseptor sel. Oleh sebab itu, gila darah tidak dapat masuk ke dalam sel. Keadaan ini dikenali sebagai "kerintangan insulin" dalam terma perubatan. Terdapat 90% pesakit kencing manis yang menghidapi diabetis Jenis 2 dan majoritinya adalah terdiri daripada orang dewasa.

Data diabetik

Apakah tahap gula darah yang dikatakan seseorang itu menghidap diabetis? WHO telah menetapkan piawai untuk mendiagnosis kencing manis:

*Tahap plasma venous gula darah ketika berpuasa adalah sama dengan atau lebih dari 7.8 mmol/L.

*Tahap plasma venous gula darah ketika kenyang adalah lebih dari 11.1mmol/L.

*Tahap gula darah ketika berpuasa iaitu 6-7mmol/L dikategorikan sebagai seseorang itu berisiko menghidapi diabetis. Ujian lanjutan diperlukan. Ujian ini dikenali sebagai " Ujian Oral Toleransi Glukosa" (OGTT)

*Proses ujian adalah: Pesakit yang berpuasa dikehendaki meminum secawan air yang mengandungi 75g glukosa. Selepas 2 jam, jika tahap glukosa darah adalah lebih daripad 11.1 mmol/L, orang tersebut menghidap diabetis.

*Jika tahap gula darah selepas 2 jam adalah disekitar 7.8mmol/L dan 11.1 mmol/L, ini bermaksud seseorang itu mempunyai risiko menghidapi penyakit kencing manis. Orang tersebut akan menjadi pesakit diabetik jika tidak bersungguh-sungguh mencari penawarnya.

Penyebab diabetis Jenis 2

Penyebab utama diabetis Jenis 1 adalah akibat kerosakan gen pankreas dan gangguan sistem keimunan. Diabetis Jenis 2 pula, lazimnya disebabkan oleh faktor-faktor berikut:

*Pengambilan jangkamasa panjang atau suntikan ubat tertentu seperti steroid.

*Diabetis dihidapi ketika hamil: Pesakit terdedah kepadadiabetis atau mederita kencing manis ketika mengandung.

*Penyakit pankreatik, seperti pankreatectomy, kanser pancreatic, pankreatitis, haemokromatosis.

*Makan terlalu banyak gula: pengambilan makanan manis setiap hari. Gangguan endokrin: muka edema, acromegaly dan neuroma pada pundi kencing.

Tanda-tanda diabetis

Kebanyakan pesakit ketika menjalani ujian darah tidak menyangka mereka menghidap kencing manis. Oleh yang demikian, dengan mengambil perhatian yang lebih, seseorang itu boleh mengetahui mereka menghidap diabetis berdasarkan simptom-simptom berikut:

*Terdapat segelintir orang Yang mengalami penurunan berat badan.

*Letih, berasa Mengantuk

*Badan mudah terdedah dengan jangkitan bakteria

*Polyuria dan polydipsia. Hal ini disebabkan gula darah memberi kesan ke atas fungsi buah pinggang iaitu penapis cecair.

*Pesakit diabetis Jenis 1 kadang kala mengalami ketoasidosis. Akibat kekurangan insulin, pesakit akan mengalami dehidrasi, kelesuan, deman, tekanan darah rendah, sesak nafas, mudah terperanjat dan mati.

Kerosakan pada buah pinggang

Diabetis akan merosakan fungsi normal buah pinggang. Bagaimana pesakit dapat megetahui bahawa buah pinggangnya rosak? Ianya dapat ditentukan dengan kehadiran 30-300mg micro-albuminuria dalam urin pada setiap 24 jam. Kehadiran albuminuria hanya dapat dikesan selepas seseorang itu menghidap kencing manis 10 hingga 15 tahun. Apabila tahap albuminuria dalam urin lebih tinggi daripada 300mg, pesakit akan menderita sakit buah pinggang dan fungsi buah pinggang akan semakin menurun. Apabila buah pinggang menjadi rosak, pesakit akan menjalani retinopathy dan menjadi buta.

Kerosakan pada sistem saraf

Diabetis akan merosakan sistem saraf dengan teruk. Kerosakan sistem saraf boleh dibahagikan kepada seksyen berikut:

*Kerosakan sistem saraf pada bahagian anggota bawah: Kaki akan berasa kebas, sakit yang beritma, kehilangan respons reflek dan otot pada kedua-dua belah kaki akan mengalami ulser kaki dan akhirnya boleh menyebabkan kematian/kelumpuhan otot.

*Neuritis kebiasaanya terjadi kepada 3 saraf, saraf dalam tengkorak, saraf pada lengan tangan dan saraf pada anggota bawah, seseorang itu akan mengalami kesakitan pada keseluruhannya.

*Kerosakan pada saraf otot. Pesakit akan mengalami amyotrophy yang mana otot akan menjadi lemah dan amat sakit.

*Autonomic neuropathies: sistem saraf autonomik adalah sistem saraf yang "membuat keputusan sendiri" dan tidak dipengaruhi oleh keadaan. Autonomik neurophaties akan menyebabkan symtom tekanan darah rendah, seperti pening kapala, impotens, Diarrhea noctumal dan keringtangan urin.

Kerosakan pada kaki

Diabetis akan menyebabkan komplikasi yang serius, yang dipanggil " kaki diabetik". Keadaan ini disebabkan oleh neuropathy dan angiopathy. Apabila ulser muncul pada kaki pesakit kencing manis, bakteria akan menceroboh tisu lembut dan tulang kaki. Cara ini menyebabkan sendi kaki akan terancam. Pada peringkat awal, saraf masih boleh merasa kesakitan tetapi kemudiannya, kaki akan menjadi kebas dan mudah tercedera. Misalnya, apabila kaki terpijak batu atau benda tajam, kaki tidak akan merasa sakit walaupun kaki tersebut berdarah sekalipun. Apabila angiopathy terbentuk pada kaki, salur darah akan menjadi sempit atau tersumbat. Jari kaki akan mula-mula sekali menerima kesannya. Apabila jari kaki berdarah, jari tersebut akan bertukar menjadi ulser. Apabila ulser semakin melarat, pesakit terpaksa dipotong (amputasi). Hal ini menunjukkan bahawa diabetis merupakan sesuatu yang membawa sinar kegelapan kepada hidup manusia.

Terjemah dari Sin Chew Daily bertarikh 21hb Mar 2006 (Bahagian 1)

Bahagian 2: Ubat kencing Manis dan kesan sampingannya

Technorati Tag: diabetis diabetik Diabetes Kencing Manis Malaysia

甜蜜杀手新动向

2006-11-21T00:14:00.000-08:00

南洋商报
报道：黄树发摄影：马耀宗

当胰岛素要将葡萄糖送到细胞内转换成能量时，需要与GTF（耐糖因子）及胰岛素受体同时产生作用，才能有效。血糖顺利进入细胞，胰岛素就可以完成一次降血糖作用。所以，GTF能增强胰岛素的生物活性、增强受体的敏感性，促进二者的亲合……透过《甜蜜杀手》糖尿病座谈会，毛嘉洪博士大谈GTF对糖尿病的最新研发动向。

人体内只要“胰岛素”、“GTF”、“胰岛素受体”三元复合体健全，唯一降血糖的激素就能发挥正常作用。对于糖尿病患者而言，有5至10%是由于缺乏胰岛素所致，约10%是缺乏胰岛素受体所致，剩下的80%是缺乏GTF所致。

台湾加特福生物科技公司董事长程伶辉表示，该公司与国立中兴大学合作，以7年时间研发出来的耐糖因子奶粉，在台湾获卫生署证明具有辅助调节血糖作用。“世界卫生组织于去年预测，未来10年内全球将有4亿人口死于糖尿病。其中2亿7千万是亚洲人，占了将近七成，因此亚洲是加特福生物科技公司走出台湾的第一个目标。

”有“生技阿妈”之称的程伶辉说：“我是因为深受糖尿病困扰，才发现投入研究治疗糖尿病的方法。研究发现糖尿病大多是因体内缺少耐糖因子导致葡萄糖不能被有效吸收所致，而耐糖因子奶粉可以成功达到辅助调节血糖的目标，进而预防及控制糖尿病。”耐糖因子奶粉已经成功销入日本、韩国、马来西亚、新加坡、印尼、汶莱、泰国。

“在台湾，虽然有数个欧美厂商或研究机构希望买断他们研发出来的技术，我拒绝了，让世界开始受惠于台湾尖端的生物科技吧！”耐糖因子奶粉于2000年获台湾国家生技医疗品质入围奖、2002年获国家生技医疗品质奖生化科技应用类品质奖、2002年获第一届国际生医新创奖、2004年又获国家生技医疗品质奖营养保健食品类金牌奖。台湾目前正进行大规模动物和人体临床试验，以期耐糖因子朝健康食品和药剂类方向发展。

缺乏耐糖因子会抑制体能和肌肉发展“

人体如果缺乏耐糖因子会抑制体能和肌肉发展，患低血糖症或第二型糖尿病的病人胰岛素功能可能减弱，导致高血脂胆固醇、诱发心脏病症。”连续饮用口服乳铁蛋白酪奶粉4个月后，糖尿病患的胰岛素敏感性获得改善，病患空腹血糖值也明显下降，且无副作用及不适现象，印证了医疗效果。耐糖因子是美国施瓦茨博士等人１９５７年从猪肾萃取发现，但一直无法量产。加特福生技公司执行总顾问毛嘉洪教授后来从人类初乳中发现耐糖因子并量产商品化。

毛嘉洪教授解释：“GTF普遍存在于人体内，维持体内糖类的正常代谢。GTF为胰岛素活化胰岛素受体所必须的物质，GTF是由微量元素三价铬离子与维生素、胺基酸所组成的复合体。正常人由食物中摄取到的‘三价铬’，可在体内转化形成GTF，进而协助葡萄糖的正常代谢。

”“若三价铬的摄取长期不足，体内自行合成的GTF 便减少。由消化系统吸收到体内的葡萄糖，即不能有效地转换成能量。高浓度的血糖流经肾无法完全被吸收，就产生糖尿病症状，而多余的葡萄糖便出现在尿液中。当血糖长期高于正常值，为了将过量的葡萄糖重吸入人体，GTF的耗损便大幅度增加。作用过后的GTF便由肾小管至尿液而排出。

”“因此，三价铬严重缺乏，使肾脏功能逐渐丧失，也是造成糖尿病的主要原因之一。”除此之外大量的劳动、怀孕、肥胖、年老、酗酒、手术或疾病等各种状况，也会增加体内铬的排出，造成铬的缺乏，导致血糖不易进入细胞而引起第二型糖尿病之临床症状。

那要如何补充GTF？“目前没有针对GTF进行量的分析，饮食中即以补充GTF核心物质——“铬离子”作为每日饮食补充GTF的指标。对铬的摄取量，一般建议每日50至200微克，但叶菜类蔬菜中的铬会与植酸结合，吸收效果欠佳；内脏类食品虽含铬量较丰富，但有胆固醇过高与抗生素残留的考虑。所以，一般人日常饮食中能从中获取的量仅约20至40微克，明显不足应付身体所需。

”加特福GT&F奶粉是模拟初乳汁功能设计，它所含之耐糖因子乃应用专利制程生产，添加于奶粉中，为接近天然、稳定之初乳含铬复合物，经由口服补充。

以下是出席者问答环节的摘录。

GT&F奶粉要吃多久才能有明显的效果？

GT&F奶粉并非药品，它是藉由饮食的形式，补充人体所需的耐糖因子，协助胰岛素发挥最佳功用。所以一般需要1到3个月的时间(因体质不同)，才能明显看到血糖下降。

糖尿病患者在补充耐糖因子之后，是否还要继续服药？

GT&F奶粉不能用来代替正规药物治疗，所以患者要继续按时服用原本的药物，不可任意停药。但是配合奶粉的服用，协助患者血糖控制更为稳定。当血糖控制越理想，医师便会减少药物用量，降低药物的副作用与身体的负担。

若GT&F奶粉和药物及胰岛素同时使用，会不会有药效过强的问题？

第2型糖尿病患者使用GT&amp;amp;amp;amp;F奶粉的反应会因人体缺乏GTF程度、个人体质、生活饮食习惯以及病龄长短等不同而有差异。糖尿病患若对GT&F奶粉调节血糖的反应较显著时，回诊时请医师依血糖检测结果，评估口服降血糖药量。

轻微糖尿病患因其原本病情即不严重，因此使用GT&F奶粉短期内并不易在血糖与血清生化值上观察到显著的差异性。而对较严重的糖尿病患，特别是已有并发症产生者，会在相关并发症上看出改善的效果，如改善其视力、行动能力等。

对于已产生肾病变而需要洗肾的糖尿病患，必须依照营养师所建议之奶制品使用量饮用GT&F奶粉，避免摄取过多磷造成肾脏负担。吃GT&F奶粉就像吃其他保健品一样，含有暝眩反应(好转反应)是正常的，会在短时期内消失。

糖尿病患者若有乳糖不耐的现象，要如何服用乳制品？

乳糖不耐多是起因于体内乳糖分泌量退化，导致无法顺利分解饮食中的乳糖而引起腹泻。如有乳糖不耐的情形，可以采分次减量的方式逐步适应，让身体的乳糖分泌量渐渐增加，则乳糖不耐的情况就会改善。

为何初期服用加特福GT&F奶粉，血糖下降相当显著，但一段时间之后，似乎就不再下降？

由于糖尿病患，体内的GTF长期缺乏，初期服用此产品，立即供应身体对耐糖因子的大量需求，配合药物治疗，胰岛素被充分活化完全发挥功用，协同血糖进入到细胞内部，所以血糖下降的情形很快速。当服用一段时间之后，体内的GTF补充到足够维持每日代谢所需，则血糖值达到一个稳定阶段，下降的情形也会逐渐缓和。这是一个正常现象。

还有其他形式的耐糖因子补充品吗？

在自然界中，牛初乳中的耐糖因子含量最为丰富；而且牛乳中所含的乳铁蛋白为耐糖因子的载体，由牛乳的形式来补充耐糖因子，是最天然也最易吸收的补充品。想要控制好血糖，必须有饮食、运动、药物三方面的全面配合，缺一不可，GTF的补充仅是其中的一环。

饮食上：饮食通常是直接反应血糖的因素，故消费者必须做好饮食控制，做到低油、低糖、低卡、避免饮酒的原则。

药物上：有病人担心降血糖药物吃太多造成对药物的依赖或是副作用，甚至错误观念认为只要饮食控制即可不需吃药，或是不按时服药，如此血糖值便会受到影响。

情绪上：情绪压力、工作忙碌、应酬过多等都会导致荷尔蒙失常，引起血糖值的失控。

运动上：每天持续性的中低强度运动，可提高身体内胰岛素的敏感性，帮助葡萄糖的代谢与利用。尤其针对肥胖病人，更可以减少脂肪堆积。

联络电话

糖因子对一般人有何帮助

a. 提升肝、肾机能，促进新陈代谢，减少疲劳感。
b. 增进葡萄糖的吸收与利用，增强体力。
c. 改善因葡萄糖代谢不良所引发的疾病。
d. 改善失眠症状，提升睡眠品质。
e. 增加葡萄糖的耐受能力，降低罹患糖尿病的机会。
Technorati Tag: 生物科技耐糖因子奶粉 Malaysia food supplement GT&F Health Chromferrin 糖尿病

Diabetes and Diabetes Complications

2006-11-21T00:07:00.000-08:00

Diabetes is called "the Mother of all Diseases".The World Health Organization (WHO) estimated that there were 250 million diabetics living around the world; resulted diabetes ranks fifth among the ten major causes of death in the world. 4 people died cause by diabetes or it complications every minutes. It is estimated that diabetics account for 6%~15% of the population in all countries. And the number of diabetics is increasing most rapidly in Asia. Cost of diabetes treatment was close to USD100 billion every year.

Asia have the highest number of diabetics patients

In 21 century, especially in 2025, diabetic Mellitus will be a formidable enemy to the health of mankind. As diabetes is the root cause of all kinds of diseases and ailments.

The World Health Organization (WHO) estimated that there were 189 million diabetics living around the world in2003. This figure is expected to sharply increase to 324 million in 2025. In other words, diabetes will increased about 72% in the next 22 years.

Asia has the highest amount of diabetes patients around the world. Increase 91% from 81.8 million in 2003 to 156.1 million in 2005.

Mejar Jeneral Dato' (Dr) Sulaiman bin Abdullah who is Director General of Health Services Malaysian Armed Forces,Health Services Division,Headquaters MAF, Ministry of Defence mentioned diabetes complications in recent interview:

Heart disease

Including Atherosclerosis and Myocardial Infarction: The risk of dying of heart disease is 2 to 4 times higher in diabetic adults compare to non-diabetic adults.

Stroke

The risk of stroke is 2 to 4 times higher in diabetic patients than in normal persons.

High Blood Pressure

It is estimeted that approximately 60 to 65% of diabetics patients have High Blood Pressure.

Kidney Failure

20 to 40% of diabetes patients have kidney disease or kidney failure or renal dialysis. Diabetes is the main cause of kidney failure.

Blindness

A leading cause of blindness among adult age between 20 to 70 is diabetic retinophathy and glaucoma.

Nerve damage

60 to 70% of diabetes patients may have certain degree of damage in circulatory and nervous system.

What is diabetes

Diabetes is a chronic disease. When the pancreas in the body is unable to secrete sufficient insulin or unable to untilize insulin effectively, leading to high sugar levels, diabetes will develop.

Hyperglycaemia and other metabolism illness may cause damage to a lot of human organ especially nerves and vascular system.

Type 1 Diabetes

Diabetes is generally divided into types I and II.

Type1 Diabetes : Usually caused by abnormal insulin production by the pancreas. Cause by human immune system killing each other cells. Approximately 10% of diabetes patients is Type 1, usually children and youths.

Type 2 Diabetes : Patients are still able to secrete insulin, but cannot effectively use insulin. The main cause of Type 2 diabetes is the reduction of insulin and insulin receptor sensitivity causing cells cannot utilize blood glucose efficiently call Insulin Resistance. Type II diabetes accounts for 90% or more of all patients, usually adult.

Diabetics Data

WHO once sets a standard to diagnose diabetes:

Patients have an empty-stomach blood sugar concentration 7.8 mmol/L may be diagnosed diabetics

Patients have a blood sugar concentration = 11.1 mmol/L at any time (including any time after meals) may be diagnosed diabetics.

If a patient's blood sugar concentration is intermediate between the two figures given above, the Oral Glucose Tolerance Test (OGTT) should be given to determine whether the patient's condition is due solely to poor glucose tolerance. If empty-stomach blood sugar is 7.8 mmol/L and blood sugar concentration is between 7.8 mmol/L and 11.1 mmol/L within two hours of taking glucose, the patient should be diagnosed as having impaired glucose tolerance (IGT). These patients may later develop diabetes if prompt preventive measures are not taken.

Cause of Type 2 diabetes

Type 1 diabetes usually caused by damage to the pancreas genes and abnormal of immune system. Type 2 diabetes usually cause by the following:

1) Prolong dependent on drug or injection: e.g.: Steroids

2) Diabetes during pregnancy.

3) Illness related to pancreas including pancreatectomy, pacreatic cancer, pancreatitis, haemochromatosis.

4) Excessive sugar intake

5) Edocrine disorder: edema of the face, acromegaly and neuroma of the urinary bladder.

Symptoms of diabetes

Some patients, by chance, during one of their blood tests, are shocked to learn that they are diabetics. Nevertheless, by paying more attention, if a person suffers from diabetes, the following symptoms will show:

1) Drop in body weight

2) Fatique, even feeling sleepy

3) Weak and easy infected by virus and bacteria

4) Excessive urine (polyuria) and thirst (polydipsia) : This is because blood sugar affects the function of the kidney that filters fluids.

5) Ketoacidosis commonly occurs in Type I diabetes patients. Low insulin may cause dehydration, exhaustion, fever, low blood pressure, short of breath, possibility of shock or even death.

Kidney Failure

Diabetes cause disorder of kidney including diabetic nephritis. A person urine have 30-300mg of Micro-Albuminuria every 24 hours. If A person have more than 10 to 15 years of diabetes history and his urine have more than 300mg of Micro-Albuminuria. He has kidney failure and require dialysis.

This may lead to diabetic retinophathy and glaucoma and cause blindness.

Nerve damage

Diabetes will seriously damage the nervous system of the patients. The damage to the nervous system can be divided into the following sections:

1) Nerve damage occur in feet , the sufferer may complain of numbness.

2) Neuritis: usually occurs on 3 nerves, which are the nerve in the skull, nerve of the arms and nerve of lower limbs, all of which will feel pain.

3) Amyotrophy

4) Autonomic Neuropathies. autonomic nervous system is the nerve system that "make it own decision" and is not affcted by willpower. autonomic neuropathaties will cause hypoglycemia (low blood pressure) like dizziness, impotence, nocturnal diarrhea and retention of urine.

Diabetic foot sores

Diabetes may cause serious complications like gangrene (or diabetic feet).

When ulcers appear on the legs of diabetic patients, bacteria will invade the soft tissues and bones of the legs. In this way, the joints of the legs become distorted. During the early stage, the nerve can still feel pain but during the late stage, the legs become numb and are easily injured, for example, when stepping a stone or protruding matter, the legs do not have any feeling even if the legs bleed. When angiopathy develops in the legs, the blood vessels become narrow or are blocked. The toes are the first affected.

When the toes bleed, the toes will ulcerated area increases, the patient are forced to have their legs amputated.

Under such circumtances, the biggest sorrow of human life is cause by diabetes.

Published by Sin Chew Daily dated 20 March 2006 (Part 1) under the courtesy of GTF Worldwide Sdn Bhd
Excerpt and translated by DiabetesMilkPowder.blogspot.com under the courtesy of DiabetesMilkPowder.com

Part 2 : Drugs for diabetes and it side effects

Technorati Tag: Biotechnology pharmaceutical Diabetes Diabetic Malaysia food supplement Health & wellness GT&F Milk Powder Chromferrin